There are Russian cruise missiles that could threaten our destroyers and their are ballistic missiles that could hit the British Airfield in Crete.
Correction Cyprus is where the airbase is. It is well within missile range and any destroyer in range of Syria for cruise missile strikes..without over flying neutral territory is vunerable to cruise missiles.
The Black Sea Fleet has added two new Sierra 2 Class Fast Attack Submarines. Those are serious war machines. They are armed with Sunburn Missiles.