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Millions told not to take pills linked to heart attacks and strokes [diclofenac]
Daily Mail ^ | 29 June 2013 | CRAIG MACKENZIE

Posted on 06/29/2013 4:23:43 AM PDT by expat1000

Doctors have been told to stop prescribing to patients with a heart condition or circulation problems one of the most commonly used anti-inflammatory drugs in the UK .

Britain's drug watchdog said the painkiller diclofenac could significantly increase the risk of a heart attack or stroke for some patients.

Millions of people take the drug for a range of conditions including arthritis, headaches, back pain and gout.

(Excerpt) Read more at dailymail.co.uk ...


TOPICS: News/Current Events
KEYWORDS: medicine; nsaid
Just my $.02 but NSAIDs seem to give little/no benefit with huge risks.
1 posted on 06/29/2013 4:23:43 AM PDT by expat1000
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To: expat1000

Pain relief is a benefit, to those suffering from pain.


2 posted on 06/29/2013 4:26:18 AM PDT by Tax-chick (I want shrimp tacos.)
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To: expat1000

“Just my $.02 but NSAIDs seem to give little/no benefit with huge risks.”

I’ve been taking Celebrex 200mg/day for about 20 years. I’d be unable to use my hands without it. But, with it and sleeping in braces, I have almost zero hand problems. I’ve had no adverse reactions. If it takes 10 years off my life, then the life I would have lived would have hurt a good deal more without the drug.


3 posted on 06/29/2013 4:27:08 AM PDT by Gen.Blather
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To: Gen.Blather

I forgot about Celebrex. It seems to be exceptionally effective.


4 posted on 06/29/2013 4:31:34 AM PDT by expat1000
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To: expat1000

My doctor prescribed Indocin for me for what I thought was a broken bone in my foot. He said the bone wasn’t broken but there was swelling that might be pinching a nerve. The pain was horrendous, almost exactly like when I broke that bone (5th metatarsil?)8 months before.

I took ONE pill and went to bed. The next morning, the pain and swelling were gone and didn’t return. I found later with the remaining pills on the prescription that my hip arthritis and other bone aches disappear when I take one at night before I go to bed. He recently gave me a longer term prescription for this use.

The only problem with them is that you must eat something before you take them or they will play hell on your stomach.

As far as I’m concerned it is a miracle drug - no pill I’ve ever taken has worked so completely and effectively. I only just found out this morning that Indomethacin is in the same family as the drug cited in the article, but it hasn’t changed my opinion.


5 posted on 06/29/2013 4:36:39 AM PDT by Gaffer
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To: Gen.Blather; expat1000; Gaffer

According to the article, diclofenac is risky for specific patients: those with heart disease, blocked arteries, smokers, etc., but has no additional risk for most people.

Also, many trashy starlets and reality-tv persons are pregnant and stuff.


6 posted on 06/29/2013 4:40:01 AM PDT by Tax-chick (I want shrimp tacos.)
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To: expat1000

Diclofenac in my opinion should never be taken orally - which is the form in question here.

Diclofenac can safely be used topically. There is a new formulation of Voltaren gel being sold OTC by Novartis in India that is about 5 times for effective than previous topical diclofenac products. It uses a tocopherol phosphate carrier to take the diclo deeper into the tissues without allowing it to reach the circulatory system.

I imagine that if sales in India are as expected, this formulation will quickly replace Novartis’ old Voltaren formulations around the world.


7 posted on 06/29/2013 4:42:16 AM PDT by John Valentine (Deep in the Heart of Texas)
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To: Gen.Blather
I’ve been taking Celebrex 200mg/day for about 20 years. I’d be unable to use my hands without it. But, with it and sleeping in braces, I have almost zero hand problems. I’ve had no adverse reactions. If it takes 10 years off my life, then the life I would have lived would have hurt a good deal more without the drug.

With most powerful drugs it's usually a cost/benefit thing. I'm the same way with asthma; the drugs might shorten my life (although they're not very powerful) but if they do I'll have considered the tradeoff to have been in my benefit.

Unfortunately there are certain busybodies out there who don't wish to give the sufferer an option in the matter.

8 posted on 06/29/2013 4:50:54 AM PDT by Mr Ramsbotham (Laws against sodomy are honored in the breech.)
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To: John Valentine

That’s good news. Does this new formulation have a unique identifier to set it apart from the old formulation?

In the US, Voltaren Gel, is a prescription product, unless that’s also changed in the past two years.


9 posted on 06/29/2013 4:56:58 AM PDT by Postman (.......................................................Boehner - Enforce the Hastert Rule!!!!)
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To: expat1000

Thanks expat100, I take diclofenac daily, will see dr next week about this.


10 posted on 06/29/2013 6:06:52 AM PDT by exbrit
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To: exbrit

You’re welcome. No harm in checking.

You might want to Google it first as well - there are some other potential problems you might want to discuss.

I guess it mostly comes down to how much relief it gives you. I’ve tried it from time to time and it didn’t give me any at all. I do use the ointment sometimes, though. As someone else on this thread suggested there’s no side effects (I think) when used topically.


11 posted on 06/29/2013 6:17:15 AM PDT by expat1000
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To: Postman

To answer your question, I don’t know. I’m assuming Novartis will market under their Voveran brand. The product is manufactured by Themis Medicare in India and is licensed by them to Novartis. I saw the announcement of this in April, but I don’t know if the product has actually hit the market yet in India.

Yes, to the best of my knowledge in the US there are no OTC diclofenac products.


12 posted on 06/29/2013 7:09:12 AM PDT by John Valentine (Deep in the Heart of Texas)
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To: Postman

To answer your question, I don’t know. I’m assuming Novartis will market under their Voveran brand. The product is manufactured by Themis Medicare in India and is licensed by them to Novartis. I saw the announcement of this in April, but I don’t know if the product has actually hit the market yet in India.

Yes, to the best of my knowledge in the US there are no OTC diclofenac products.


13 posted on 06/29/2013 7:09:29 AM PDT by John Valentine (Deep in the Heart of Texas)
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To: John Valentine

Oh great... I’ve been taking it for years..

But, only sparingly... I take it before I play golf. So, probably refill my 30 pills 1-2 times a year.

Now what will I do? And, DON’T SAY “lose weight”!


14 posted on 06/29/2013 7:18:33 AM PDT by SomeCallMeTim ( The best minds are not in government. If any were, business would hire them f)
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To: expat1000

The best anti-inflammatory I’ve ever taken is BROMELAIN. It’s made from an ingredient in pineapples.


15 posted on 06/29/2013 7:46:59 AM PDT by aimhigh (Guns do not kill people. Abortion kills people.)
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To: Gen.Blather

Have tried MSM?


16 posted on 06/29/2013 7:51:24 AM PDT by Captain Peter Blood
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To: Captain Peter Blood

“Have tried MSM?”

What is MSM?


17 posted on 06/29/2013 7:53:39 AM PDT by Gen.Blather
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To: expat1000

I take an NSAID every day. Couldn’t work or play with my kids without it. Many drugs have heightened risks for those who are already sick. Unfortunately, for chronic pain sufferers like myself there will probably be an effort to take these effective (and cheap!) medications off the market.


18 posted on 06/29/2013 7:55:59 AM PDT by Straight Vermonter (Posting from deep behind the Maple Curtain)
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To: Gen.Blather
It's a dietary supplement that can help with joint, connective tissue and cartilage.
James Coburn, the actor, had severe Rheumatoid Arthritis pain in his body and got to the point he could not work and he tried everything. Someone put him on to MSM and it worked and allowed him to work again.
I have used it for hip and joint pain in the past and recently have noticed creeping arthritis in my hands and I am back on it and notice a difference already after only a few days.
You might look into it for your hands and maybe you can ease off the Celebrex. Plenty of info out there.
19 posted on 06/29/2013 8:11:05 AM PDT by Captain Peter Blood
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To: Straight Vermonter

>>Many drugs have heightened risks for those who are already sick.

Certainly, but NSAIDs are also one of primary causes of stomach/peptic ulcers. There are always trade-offs.


20 posted on 06/29/2013 8:15:43 AM PDT by expat1000
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To: Captain Peter Blood

“It’s a dietary supplement that can help with joint,”

Is there an actual name? I’d hate to be supplementing with mainstream media. It’d probably give me a pain in the posterior.


21 posted on 06/29/2013 9:58:54 AM PDT by Gen.Blather
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To: expat1000
There are always trade-offs.

Of course but living in pain is not really an option. People that do not have chronic pain never seem to understand that.

22 posted on 06/29/2013 12:19:42 PM PDT by Straight Vermonter (Posting from deep behind the Maple Curtain)
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To: John Valentine

Thanks very much for the reply. I’ll check with Novartis from time to time.


23 posted on 06/29/2013 5:38:16 PM PDT by Postman (.......................................................Boehner - Enforce the Hastert Rule!!!!)
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To: Gen.Blather

It’s called Methylsulphonylmethane
Just type in MSM on the internet and you will find all the info you want.


24 posted on 06/30/2013 7:55:31 AM PDT by Captain Peter Blood
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