Why not a techno thriller that allows the last christian holdouts left on earth that have taken refuge underground in Antarctica for several decades and chance upon secret Third Reich weapons so far advanced many speculated Hitler gained some form of alien technology.
And these last Christians on earth battle an Islamic domination globally, they program a nanobot that targets Moslems first off, the device causes any person praying certain Islamic phrases to go into a 3 day coma. That is just a warning.
Any moslem screaming “All our snackbars” or similar wordage has an immediate and uncontrollable heavy dose of diarrhea.
A black hole develops at Mecca and it basically disappears.
And then eventually billions of robotic insects fly around globally everywhere looking for any words about Islam and then attack by burrowing into the persons skull and exploding.
Islam dies along with about a billion people, peace then develops, mankind is free again.
Sounds like a good plot for a novel.
I seem to remember reading some novel where a particular strain of ebola was made that affected those of middle eastern descent.