If you come across something that you believe is actually preventative or slowing regarding Alzheimer’s I’d appreciate it if you’d ping me. My mother has it and my father’s sister had it.
Curcuminoids, it does work in my opinion based upon what I’ve read and studied. It’s just hard to get enough of it into their system. My knowledge is four going on five years old. Patches stained skin yellow. Sublingual, meaning a liquid placed under the tongue for absorption, seemed more promising but still wasn’t completely practical at the time. Could be by now though. I’ll do a quick search to see what’s what as of now.
So-called liposomal curcumin appears to be a sort of caveat emptor situation, as there are a number of companies claiming to offer it and that their product uniquely enhances bioavailability. Liposomal curcuminoids, the genuine article from clinical trials, was patented by UCLA researchers and I do not see that it is readily available at present. That doesn't mean that it isn't, just that I didn't see it.
As far as how much, I'm not able or willing to make that recommendation. Curcumin taken as a supplement is usually regarded as dose to tolerance since toxicity has not been noted and digestive distress/diarrhea is the worst thing to expect from a large dose that I'm aware, but again please research this and validate for yourself.
There are potential conditions that can be aggravated by it though, gallstones, etc. but the most notable thing to watch out for and to avoid is drug interactions, it's right up there with grapefruit for that sort if thing.
As far as reliable sources of information found online, I'd rely on clinical trials, PubMed and the like. There are also several patent applications with useful information, but the majority deal specifically with increasing bioavailability with treatment of various forms of cancer as the objective. All of these will involve slogging through a lot of jargon with which you'll need to become at least somewhat familiar, or find a knowledgeable person who is familiar and is willing to help you out.
Piperine is another thing that has been shown to increase bioavailability and absorption of curcuminoids but I've seen nothing dealing with this in combination with DHA.
Please use your best judgment, don't take anybody’s word as gospel until you've researched and verified and proceed carefully if you do decide to take this further. Discuss it with a doctor before you do. Some are favorable and sympathetic, others aren't.
Here’s a link with a fair amount of info: