There’s one huge difference between the rats they use in these studies and the people they ultimately hope will benefit from these drugs - the rats eat food.
Most people eat processed crap that has only a vague resemblance to actual food.
It may be that these drugs might have some benefit, but I’d be very surprised if they’d be powerful enough to the thousands of calories of junk people eat every day.
No economy could sustain any significant population at that extreme age. Look at the situation we have now...
Imagine having to listen to Jimmy Carter natter on about his crap for another 70 years.
“Grandfather, it’s not healthy to live to be such an old age” {Windwalker}
Absolute total disaster unless they are able to stop all dementia, Alzheimers, and related neurological breakdowns first.
I can not imagine dealing with a dementia patient for 80+ years.