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Grapefruit Interacting Drugs and Associated Oral Bioavailability, Adverse Event(s), Risk Ranking and Potential Alternative Medications(PDF)

Type 2 diabetics taking repaglinide, aka Prandin, and saxagliptin, aka Onglyza, beware of the mentioned foods.

1 posted on 12/18/2012 8:13:19 PM PST by neverdem
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To: neverdem

Maybe John Boenher will suggest we have a frank discussion about citrus.


2 posted on 12/18/2012 8:19:22 PM PST by SpaceBar
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To: neverdem

I’m not sure if suggesting a smaller amount of medication plus grapefruit juice, as a cost saver, would be a joke or not. I’d guess that the grapefruit juice would have to be pretty well calibrated as well, not just something from the grocery store.


3 posted on 12/18/2012 8:22:03 PM PST by jiggyboy (Ten percent of poll respondents are either lying or insane)
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To: neverdem
Grapefruit Is a Culprit in More Drug Reactions

That's why it is a good idea to read the pamphlets included with your medications.

4 posted on 12/18/2012 8:24:01 PM PST by Alaska Wolf (Carry a Gun, It's a Lighter Burden Than Regret)
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To: neverdem

I don’t eat or drink grapefruit, but I do drink a bit of orange juice at breakfast. I’ll have to check that out, I guess, since I take atorvastatin.


5 posted on 12/18/2012 8:30:18 PM PST by Cicero (Marcus Tullius)
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To: neverdem

Thank you for this. I had known that grapefruit juice and other citrus interferes with some drugs, but didn’t know about the statins.


6 posted on 12/18/2012 8:33:08 PM PST by MestaMachine (It's the !!!!TREASON!!!!, stupid!)
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To: neverdem
I'm on Lipitor and the instructions say not to have grapefruit juice. I really miss grapefruit juice - I don't have a sweet tooth - I have an anti-sweet tooth. I was also on verapamil for a while.



Keep Faith with the Fallen of Benghazi! Let the Obama Regime, for once, tell the Truth!

Fiat Justitia, Ruat Coelum!

Genuflectimus non ad principem sed ad Principem Pacis!

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7 posted on 12/18/2012 8:41:14 PM PST by ConorMacNessa (HM/2 USN, 3/5 Marines RVN 1969 - St. Michael the Archangel defend us in Battle!)
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To: neverdem

It is interesting since Grapefruit juice is my least favorite type of juice and I’ve very rarely had it. Grapefruit sparkling water, on the other hand I’ve indulged in that more.


8 posted on 12/18/2012 8:48:16 PM PST by Merta (I blame Adam)
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To: neverdem
From MedicineNet.com: Large quantities of grape fruit juice (>1 quart daily) also will increase blood levels of simvastatin and should be avoided.
9 posted on 12/18/2012 8:51:05 PM PST by Brandonmark (OWCM is The new American Minority!)
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To: Judith Anne; 2ndreconmarine; Fitzcarraldo; Covenantor; rejoicing; Rushmore Rocks; ...

Health & science stories like this one is one of the few reasons I check out the NY Times. Most patients are unaware of adverse food and drug interactions, unless it’s printed on the label of the drug container.

This one of those rare everybody on my lists gets pinged, including some medical docs who have identified themselves as such that are not on any list. Comment# 1 has a link to the list of these drugs. From its URL it looks like it was in the Journal of the Canadian Medical Association.

Happy Chanukah, Merry Christmas and Happy New Year!


10 posted on 12/18/2012 8:53:59 PM PST by neverdem ( Xin loi min oi)
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To: Judith Anne; 2ndreconmarine; Fitzcarraldo; Covenantor; rejoicing; Rushmore Rocks; ...

Health & science stories like this one is one of the few reasons I check out the NY Times. Most patients are unaware of adverse food and drug interactions, unless it’s printed on the label of the drug container.

This one of those rare everybody on my lists gets pinged, including some medical docs who have identified themselves as such that are not on any list. Comment# 1 has a link to the list of these drugs. From its URL it looks like it was in the Journal of the Canadian Medical Association.

Happy Chanukah, Merry Christmas and Happy New Year!


11 posted on 12/18/2012 8:54:59 PM PST by neverdem ( Xin loi min oi)
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To: neverdem

A while back, someone who was a medical transcriber told me, that, grapefruit juice was a trick older folks used with their meds to save money. They’d take half the dose prescribed with a glass of grapefruit juice. The medical establishment would frown on that because they would lose money... and it would mess up their statistics.

I don’t know how much of that is true.


12 posted on 12/18/2012 8:59:33 PM PST by 1_Rain_Drop
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To: neverdem

13 posted on 12/18/2012 9:00:01 PM PST by Revolting cat! (Bad things are wrong! Ice cream is delicious!)
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To: neverdem; a fool in paradise; Slings and Arrows

14 posted on 12/18/2012 9:01:02 PM PST by Revolting cat! (Bad things are wrong! Ice cream is delicious!)
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To: neverdem
Since grapefruit juice is cheaper than prescription drugs - maybe a smaller dose and a glass of juice would be a better idea...
17 posted on 12/18/2012 9:07:52 PM PST by GOPJ (Detroit should be renamed 'Michael Mooresville'...)
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To: neverdem
Per the Mayo Clinic website:
Certain chemicals that grapefruit products and citrus fruits contain can interfere with the enzymes that break down (metabolize) various medications in your digestive system. As a result, more medication stays in your body. This can increase the potency of your medication to potentially dangerous levels, causing serious side effects.

23 posted on 12/18/2012 9:25:47 PM PST by Brandonmark (OWCM is The new American Minority!)
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To: neverdem

I’m warned not to eat natural licorice while taking my B.P. medication. Until I read that I wasn’t even aware that there was a “natural” and “unnatural” licorice.


24 posted on 12/18/2012 9:26:54 PM PST by Graybeard58 ("Civil rights” leader and MSNB-Hee Haw host Al Sharpton - Larry Elder)
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To: neverdem

They finally have a safe drug that cures everything:
http://www.youtube.com/watch?v=EP9B3NBFD2M


26 posted on 12/18/2012 9:35:18 PM PST by Born to Conserve
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To: neverdem

Earl Grey Tea also has a reaction with medications. You have to read the box and medication literature to find that out.


31 posted on 12/18/2012 10:07:55 PM PST by petitfour
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To: neverdem

Red Grapefruit juice is my favorite juice to mix with club soda. However, since I take verapamil, I just don’t do grapefruit other than maybe once a year.

Lately my blood pressure has trended up, so maybe I should treat my self a little and have 1/4 or 1/2 cup. LOL.


34 posted on 12/18/2012 11:25:38 PM PST by greeneyes (Moderation in defense of your country is NO virtue. Let Freedom Ring.)
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To: neverdem

!!!!

Wowzers.


36 posted on 12/19/2012 4:56:05 AM PST by Darksheare (Try my coffee, first one's free.....)
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