Skip to comments.Discovery of 100 million-year-old regions of DNA shows short cut to crop science advances
Posted on 12/17/2012 10:15:21 PM PST by neverdem
Scientists have discovered 100 million-year-old regions in the DNA of several plant species which could hold secrets about how specific genes are turned 'on' or 'off'.
The findings, which are hoped will accelerate the pace of research into crop science and food security, are detailed by University of Warwick researchers in the journal The Plant Cell.
By running a computational analysis of the genomes of the papaya, poplar, Arabidopsis and grape species, scientists have uncovered hundreds of conserved non-coding sequences which are found in the DNA of all four species.
These non-coding sequences are not genes, but are located in the promoters upstream of genes and are around 100 DNA base pairs in length.
As the four species have evolved separately for around 100 million years, the fact that these regions have been conserved suggests they play an important role in the plants' development and functioning.
The team at the University of Warwick believe these regions are involved in controlling the expression of the genes they are upstream of - in other words determining whether the genes are turned 'on' or 'off' according to the environmental conditions or developmental stage of the plant.
For example, some genes will be required for defence against pathogens, or others will be required for germination.
Dr Sascha Ott of the Warwick Systems Biology Centre said: "We know that certain genes are conserved between species but we also see that sequences outside of genes are conserved.
"The regions outside genes that we have discovered have been kept for millions and millions of years across four species.
"There must be a reason for this if something has been around for so long it is probably useful in some way.
"We believe it may be because these regions have a very important role to play in how the plant develops and functions.
"It is likely that they are involved in controlling gene expression a vital area for scientists to study as it will ultimately help us to develop crops with specific properties, for example drought tolerance.
"By pinpointing these specific regions, we have zoomed in on what seems to be a very old, and very important, part of DNA.
"We have opened up a short-cut as with this information, the biology community can now focus their experiments on specific regions next to genes which are key targets for plant breeding, and could play an important part in addressing the issue of food security.
"This discovery can be used to underpin future research focusing on working out regulatory codes and link sequence patterns to expression patterns." Source : University of Warwick
Anyone interested in this area of science should be sure to read “Endless Forms Most Beautiful” by Sean Carroll (sp?).
DNA is the worst spaghetti code imaginable in terms that it is not meant to be read by humans. Making just small alterations can have unforeseen consequences in a million differnt parts of the “program”. You make one disease-resistant plant with a few hacker lines and end up with man-eating tomatos.
Yeah, sounds like a great MOVIE, lets call it “attack of the killer tomatoes”
Yeah, sounds like a great MOVIE, lets call it “attack of the killer tomatos”
I’m not really interested in eating food somebody else has played with.
That’s funny. I was just musing about how I might learn enough DNA engineering to alter how my garden plants grow. DIY in this area could be a huge industry and would sure be a lot of fun. For instance, I’d grow 5-pound tomatoes which would make canning a lot easier. And if they turned out to be man-eating mutants, I’d plant them along my neighbors border and in the front yard to keep dogs from crapping there.
|GGG managers are SunkenCiv, StayAt HomeMother & Ernest_at_the_Beach|
No wonder my DNA feels old today. Thanks gleeaikin.
Thanks, have you read the book or do you plan to. Let me know what you think if you do.
I read an article recently suggesting that an important factor in current obesity issues is from hybrid wheat. It said there is some genetic change that effects how the body perceives or stores after eating wheat. I wish I could find the article.
I haven't read it, but I find my interest piqued and now likely will, and will let you know my thoughts on it if/when I do. Hopefully it's not above my intellectual pay grade.
SunkenCiv: I'd like to get on the GGG Ping list, if it's not too much trouble.
I’m happy to add you to the GGG list, note however that I stopped pinging it about two weeks ago, and discontinued the weekly digest as well. Anyway, welcome!