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New Bacteria Raises Concern
KDLT ^ | November 29, 2012 | Laura Monteverdi

Posted on 12/03/2012 1:31:48 AM PST by neverdem

A deadly bacteria known as Carbapenem-Resistant Enterobacteriaceae, or CRE, is raising concerns in the medical community.

Jennifer Hsu in an Infectious Disease Physician at Sanford Health and has been closely studying this 'super bug' which is best known for it's ability to defy even the strongest of drugs.

“What has happened over time with increasing exposure to antibiotics the bacteria have developed ways to evade those antibiotics and they become resist to a certain class of antibiotics,” said Hsu.

In the United States, the bacteria have been found primarily in healthcare facilities and hospitals and are known to prey on the weak.

“Patients who are immune-compromised whether it be from medical treatments, chemotherapy for instance or patients that have had other severe illnesses that place them in the ICU-those would be risk factors,” said Hsu.

CRE infections are already an epidemic in several major cities including New York and Chicago, but Hsu said not to be surprised if we start to see them more frequently in less-populated areas.

“There's no reason to think that we won't see them in South Dakota and they won’t become increasingly common here but really our goal is to head that off before it happens,” said Hsu.

Experts said that there isn't likely to be a vaccine for this type of infection, but they are continually researching ways to prevent it from spreading. While doctors are fighting hard to keep it contained, it may be a battle they are not equipped to win.

"There is absolutely no reason to think that if we don't do a good job with infection control that this is going to stay in a hospital,” said Hsu.

Which may mean this 'super bug' is here to stay,always close-by and always a threat.


TOPICS: Culture/Society; News/Current Events
KEYWORDS: antibioticresistance; bacteria; cre; epidemic; medicine; micobiology; outbreak; superbug
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Deadly 'superbugs' invade U.S. health care facilities
1 posted on 12/03/2012 1:31:58 AM PST by neverdem
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To: neverdem

With Obamacare taking effect, across the land, you won’t live long enough to worry about superbugs.


2 posted on 12/03/2012 1:41:59 AM PST by Jonty30 (What Islam and secularism have in common is that they are both death cults.)
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To: 2ndreconmarine; Fitzcarraldo; Covenantor; Mother Abigail; EBH; Dog Gone; ...

Ping... (Better late than never, and thanks for posting, neverdem!)


3 posted on 12/03/2012 1:49:54 AM PST by Smokin' Joe (How often God must weep at humans' folly. Stand fast. God knows what He is doing)
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To: 2ndreconmarine; Fitzcarraldo; Covenantor; Mother Abigail; EBH; Dog Gone; ...

Ping... (Better late than never, and thanks for posting, neverdem!)


4 posted on 12/03/2012 1:50:23 AM PST by Smokin' Joe (How often God must weep at humans' folly. Stand fast. God knows what He is doing)
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Comment #5 Removed by Moderator

To: Admin Moderator
I only tried to post that ping once, and I got the following message on the page, with the URL

http://www.freerepublic.com/perl/post

An error occurred.

Sorry, the page you are looking for is currently unavailable.

Please try again later.

If you are the system administrator of this resource then you should check the error log for details.

Faithfully yours, nginx.

Just hoping that might help do away with some of the multiple posts around here.

6 posted on 12/03/2012 2:01:24 AM PST by Smokin' Joe (How often God must weep at humans' folly. Stand fast. God knows what He is doing)
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To: Admin Moderator

The error log URL (HTML imbedded link) http://nginx.org/r/error_log


7 posted on 12/03/2012 2:02:54 AM PST by Smokin' Joe (How often God must weep at humans' folly. Stand fast. God knows what He is doing)
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To: neverdem

I don’t read anything by anyone who doesn’t know when to say “bacteria” and when to say “bacterium.”


8 posted on 12/03/2012 2:25:29 AM PST by Arthur McGowan (If you're FOR sticking scissors in a baby girl's neck and sucking out her brains, you are PRO-WOMAN!)
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To: neverdem

NDM-1 stands for New Delhi metallo-beta-lactamase, which is an enzyme produced by certain strains of bacteria that have recently acquired the genetic ability to make this compound. The enzyme is active against other compounds that contain a chemical structure known as a beta-lactam ring. Unfortunately, many antibiotics contain this ring, including the penicillins, cephalosporins, and the carbapenems.

NDM-1 infection was first identified (in 2009) in people who resided in or traveled to the India and Pakistan. Antibiotic use in India is not as restricted as it is in the United States and some researchers feel overuse of carbapenems allowed NDM-1 to develop. Others point to the advent of medical tourism as a cause of NDM-1 spread among countries. Medical tourism refers to patients who travel to a country to get medical care that is not available or is more expensive in their own country. The three first cases of NDM-1 infection in the United States were identified in June 2010 in Americans who had recently sought medical care in India. Vacation and business travel have also played a role in introducing NDM-1 bacteria into countries outside of the Indian subcontinent. Cases have now been detected in many countries, including Great Britain, Canada, Sweden, Australia, Japan, and the United States.

Cases of NDM-1 infection are usually caused by gram negative bacteria from the Enterobacteriaceae family. This family includes common bacteria like Escherichia coli (E. coli) and Klebsiella. These bacteria reside in the bowel and may spread from person to person if hands or items are contaminated with fecal material. To date, strains of Klebsiella, Escherichia, and Acinetobacter genera of bacteria are known to possess the gene for NDM-1.

What are symptoms and signs of a person infected with bacteria carrying NDM-1?

Bacteria from the Enterobacteriaceae family are the most common cause of urinary infections. They can also cause bloodstream infections (sepsis), pneumonia, or wound infections. Symptoms and signs reflect the site of the infection. Most patients will have fever and fatigue. If bacteria enter the bloodstream, patients may go into shock. Symptoms do not differ between bacteria that express NDM-1 and those that do not. However, patients who have bacteria producing NDM-1 will not respond to most conventional antibiotics and are at high risk for complications.

Centers for Disease Control and Prevention
“Detection of Enterobacteriaceae Isolates Carrying Metallo-Beta-Lactamase -— United States, 2010.” http://www.cdc.gov/mmwr/preview/
mmwrhtml/mm5924a5.htm

Centers for Disease Control and Prevention
“Guidance for Control of Infections with Carbapenem-Resistant or Carbapenemase-Producing Enterobacteriaceae in Acute Care Facilities.” http://www.cdc.gov/mmwr/preview/mmwrhtml/mm5810a4.htm


9 posted on 12/03/2012 3:57:24 AM PST by tired&retired
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To: tired&retired

Carbapenem-resistant Enterobacteriaceae (CRE)

The term CRE refers to carbapenem-resistant and carbapenemase-producing Enterobacteriaceae. Currently, the most common type of carbapenemase in the United States is the Klebsiella pneumoniae carbapenemase (KPC). In 2010, carbapenemases known as metallo-beta-lactamases (MBL) were first detected in the U.S.: New Delhi MBL (known as NDM-1) and Verona-Integron encoded MBL (known as VIM).

Clinical significance

K. pneumoniae can cause the disease Klebsiella pneumonia.

They cause destructive changes to human lungs inflammation and hemorrhage with cell death (necrosis) that sometimes produces a thick, bloody, mucoid sputum (currant jelly sputum). Typically these bacteria gain access after a person aspirates colonizing oropharyngeal microbes into the lower respiratory tract.

As a general rule, Klebsiella infections are mostly seen in people with a weakened immune system. Most often illness affects middle-aged and older men with debilitating diseases. This patient population is believed to have impaired respiratory host defenses, including persons with diabetes, alcoholism, malignancy, liver disease, Chronic obstructive pulmonary diseases (COPD), glucocorticoid therapy, renal failure, and certain occupational exposures (such as paper mill workers).

Many of these infections are obtained when a person is in the hospital for some other reason (a nosocomial infection).

The most common infection caused by Klebsiella bacteria outside the hospital is pneumonia, typically in the form of bronchopneumonia and also bronchitis. These patients have an increased tendency to develop lung abscess, cavitation, empyema, and pleural adhesions. It has a high death rate of about 50% even with antimicrobial therapy. The mortality rate can be nearly 100% for persons with alcoholism and bacteremia.

In addition to pneumonia, Klebsiella can also cause infections in the urinary tract, lower biliary tract, and surgical wound sites. The range of clinical diseases includes pneumonia, thrombophlebitis, urinary tract infection (UTI), cholecystitis, diarrhea, upper respiratory tract infection, wound infection, osteomyelitis, meningitis, and bacteremia and septicemia. If a person has an invasive device in their body then contamination of the device becomes a risk; for example respiratory support equipment and urinary catheters put patients at increased risk.

Also, the use of antibiotics can be a factor that increases the risk of nosocomial infection with Klebsiella bacteria. Sepsis and septic shock can follow entry of the bacteria into the blood.


10 posted on 12/03/2012 4:09:49 AM PST by tired&retired
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To: tired&retired

The extent and prevalence of CRKP within the environment is currently unknown. The mortality rate is also unknown but is suspected to be within a range of 12.5% to as high as 44%.

The likelihood of an epidemic or pandemic in the future remains uncertain.

Over the past 10 years, a progressive increase in CRKP has been seen worldwide; however, this new emerging nosocomial pathogen is probably best known for an outbreak in Israel that began around 2006 within the healthcare system there.

In the USA, it was first described in North Carolina in 1996; since then CRKP has been identified in 41 states; and is recovered routinely in certain hospitals in New York and New Jersey. It is now the most common CRE species encountered within the United States.


11 posted on 12/03/2012 4:13:59 AM PST by tired&retired
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To: Arthur McGowan

“I don’t read anything by anyone who doesn’t know when to say “bacteria” and when to say “bacterium.””

For those who do not understand your comment.

Bacteria is the plural of bacterium, and that saying “a bacteria” is incorrect. It is correct to say “The soil sample contains millions of bacteria,” and “Tetanus is caused by a bacterium.”


12 posted on 12/03/2012 4:18:00 AM PST by tired&retired
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To: neverdem

“Experts said that there isn’t likely to be a vaccine for this type of infection, ...” Experts?


13 posted on 12/03/2012 5:10:43 AM PST by meatloaf (Support Senate S 1863 & House Bill 1380 to eliminate oil slavery.)
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To: neverdem

Not only is it super bugs, but these diets for cholesterol cause deficiencies in Iodine, and the new sea salt craze just adds to it, and when the doctors throw in a low sodium diet you are screwed.
Eggs, cheese and meat beyond iodized salt are the main sources of Iodine. Read a label and you won’t find the word Iodine on it. And with the new ‘truth in labeling law’ it has to be listed even if it provides 0 nutrition.

Ask my thyroid what these two waring diets did to it. Took and Endocrinologist to fix the mess the PCP and the ENT created.


14 posted on 12/03/2012 5:30:05 AM PST by GailA (those who do not keep promises to Military, won't keep them to U)
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To: Smokin' Joe

When you get that message, your reply probably did go through.

It’s a good practice to checks your pings or refresh the thread to see if it did post before attempting to post it again.


15 posted on 12/03/2012 5:33:04 AM PST by Admin Moderator
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To: Admin Moderator
I only clicked the post button once. The message came up, and I checked to see if the ping had gone through in another window. It had--three times--one click.

I have noticed a lot of others who are pinging people are getting triples too, and thought I'd pass that info on.

16 posted on 12/03/2012 5:42:06 AM PST by Smokin' Joe (How often God must weep at humans' folly. Stand fast. God knows what He is doing)
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To: neverdem

Bump to that USA Today article. Excellent for a lib publication.


17 posted on 12/03/2012 6:07:57 AM PST by upchuck (America's at an awkward stage. Too late to work within the system, too early to shoot the bastards.)
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To: GailA
Not only is it super bugs, but these diets for cholesterol cause deficiencies in Iodine, and the new sea salt craze just adds to it, and when the doctors throw in a low sodium diet you are screwed.

Don't forget the increasing prevalence of vaccination for every ailment under the sun, which diverts the immunity and is probably particularly dangerous for persons whose immunity is already compromised.

18 posted on 12/03/2012 6:11:06 AM PST by Mr Ramsbotham (Laws against sodomy are honored in the breech.)
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To: Smokin' Joe

Double posts from one click on the post button have the exact same time stamp, right down to the second.

Yours is indeed a strange glitch.


19 posted on 12/03/2012 6:13:21 AM PST by Admin Moderator
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To: neverdem

I am generally suspicious of primarily “nosocomial”, or hospital acquired infections, for the simple reason that hospitals are not particularly septic compared to many other places, such as prisons, locker rooms, etc.

If a pathogen is strong enough to be nosocomial, then it should be rampant in those other places.

Instead, suspicion should first fall on improper administration of antibiotics. There is still no disciplined doctrine for their proper use, so prescription varies widely between doctors.

Importantly, often when strict discipline is imposed, the number of nosocomial patients drops drastically.


20 posted on 12/03/2012 6:22:56 AM PST by yefragetuwrabrumuy (Pennies and Nickels will NO LONGER be Minted as of 1/1/13 - Tim Geithner, US Treasury Sect)
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To: Admin Moderator
That's why I brought it up, and it doesn't generally happen when I only reply to one person. When I ping a list, though, error messages are common enough that I have made it a habit of opening the thread in another window or tab and checking to see if the ping went through.

This time, the error message looked different, and I got a triple post.

21 posted on 12/03/2012 6:26:47 AM PST by Smokin' Joe (How often God must weep at humans' folly. Stand fast. God knows what He is doing)
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To: neverdem

By all means lets keep injecting cattle, etc., with gargantuan amounts of anti-biotics until anti-biotics are rendered completely useless. Got a dangerous tooth infection that requires anti-biotics? Too bad, so sad. You will just have to die from the infection. And store shelves are still crammed with anti-bacterial soaps, etc. And doctors still give out anti-biotics like candy, even for non serious things.


22 posted on 12/03/2012 6:36:53 AM PST by chessplayer
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To: Smokin' Joe

Thanks for the ping!


23 posted on 12/03/2012 6:45:28 AM PST by Alamo-Girl
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To: Alamo-Girl

You’re Welcome, Alamo-Girl!


24 posted on 12/03/2012 6:49:57 AM PST by Smokin' Joe (How often God must weep at humans' folly. Stand fast. God knows what He is doing)
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To: neverdem; 1000 silverlings; Alex Murphy; bkaycee; blue-duncan; boatbums; caww; count-your-change; ..

ping


25 posted on 12/03/2012 7:02:08 AM PST by metmom (For freedom Christ has set us free; stand firm therefore & do not submit again to a yoke of slavery)
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To: Mr Ramsbotham

And parents making their kids live in a “plastic bubble” by making them avoid playing in dirt.......your immune system is like a muscle, “Use it, or lose it.”


26 posted on 12/03/2012 7:05:41 AM PST by dfwgator
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To: neverdem

Too bad the scientists didn’t name this bug after Obama.


27 posted on 12/03/2012 7:55:29 AM PST by moovova
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To: neverdem

Andromeda strain reprise.


28 posted on 12/03/2012 8:26:25 AM PST by YHAOS
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To: Jonty30

Invest in painkillers.


29 posted on 12/03/2012 11:46:44 AM PST by DPMD
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To: metmom

How interesting. I fear we are going to be hearing about more of these sorts of things.


30 posted on 12/03/2012 2:26:56 PM PST by CynicalBear
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To: tired&retired

Thanks for the comments & links.


31 posted on 12/03/2012 2:54:47 PM PST by neverdem ( Xin loi min oi)
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To: Admin Moderator
Double posts from one click on the post button have the exact same time stamp, right down to the second.

55 posted on Mon Dec 03 2012 19:20:39 GMT-0200
56 posted on Mon Dec 03 2012 19:21:37 GMT-0200
57 posted on Mon Dec 03 2012 19:22:38 GMT-0200

That was a single click on

http://www.freerepublic.com/focus/news/2965075/posts?page=55#55

FWIW, Adios

32 posted on 12/03/2012 3:14:51 PM PST by neverdem ( Xin loi min oi)
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To: neverdem

...as if we don’t have enough to worry about!


33 posted on 12/03/2012 3:19:04 PM PST by miserare
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To: neverdem

Impossible! I have been repeatedly told that there is no such thing as evolution, evolutionary change is not science, that all change will make an organism less fit as it changes it away from the way God created it; so there couldn’t possibly be a “New Bacteria” that is antibiotic resistant!/s


34 posted on 12/03/2012 3:25:37 PM PST by allmendream (Tea Party did not send GOP to D.C. to negotiate the terms of our surrender to socialism)
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To: neverdem
The very nasty consequences of antibiotic misuse. Ignorant patients insist on antibiotics from their doctors, even when that's the wrong medication.

Doctors who prescribe antibiotics for viral infections should lose their medical licenses.

Immigrants from countries where antibiotics are available over-the-counter should be denied entry into the country.

Antibiotic resistant bacteria are serious, but nobody seems to be willing to deal with it that way!

35 posted on 12/03/2012 3:42:53 PM PST by TChris ("Hello", the politician lied.)
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To: TChris
This could very well be what killed Savita Halappanavar....

I'm just noting that abortion is not a cure for septicemia.

36 posted on 12/03/2012 3:46:51 PM PST by Mrs. Don-o (Honest to God.)
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To: TChris
This could very well be what killed Savita Halappanavar....

I'm just noting that abortion is not a cure for septicemia.

37 posted on 12/03/2012 4:00:00 PM PST by Mrs. Don-o (Honest to God.)
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To: TChris
This could very well be what killed Savita Halappanavar....

I'm just noting that abortion is not a cure for septicemia.

38 posted on 12/03/2012 4:00:09 PM PST by Mrs. Don-o (Honest to God.)
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To: Mrs. Don-o

Regarding your recent triple post on this thread, did you click once or 3 times? I’m just curious because some people think double and triple posts happen when ping lists are used.


39 posted on 12/03/2012 4:35:02 PM PST by neverdem ( Xin loi min oi)
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To: neverdem

Actually? I clicked once. Don’ know how that happened.


40 posted on 12/03/2012 4:52:57 PM PST by Mrs. Don-o (Honest to God.)
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To: allmendream; GodGunsGuts; Fichori; tpanther; Gordon Greene; Ethan Clive Osgoode; betty boop; ...
I have been repeatedly told that there is no such thing as evolution, evolutionary change is not science, that all change will make an organism less fit as it changes it away from the way God created it; so there couldn’t possibly be a “New Bacteria” that is antibiotic resistant!/s

It's not a new bacteria. It's an old one which is an anti-biotic resistant strain.

Don't you believe in variation within species? What kind of scientist are you?

Do you also think blond haired people are a different species than black haired people? Sheesh.......

41 posted on 12/03/2012 7:50:22 PM PST by metmom (For freedom Christ has set us free; stand firm therefore & do not submit again to a yoke of slavery)
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To: neverdem

There’s been a ton of double and triple posts lately. It does seem to happen more with ping lists, but I’ve had it happen when just posting responses as well.


42 posted on 12/03/2012 7:52:27 PM PST by metmom (For freedom Christ has set us free; stand firm therefore & do not submit again to a yoke of slavery)
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To: metmom

LOLOL!


43 posted on 12/03/2012 9:09:46 PM PST by Alamo-Girl
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To: metmom

So your premise is that the antibiotic resistance existed before the antibiotic was invented? An interesting, if idiotic, supposition. At least you are consistent!


44 posted on 12/03/2012 9:13:56 PM PST by allmendream (Tea Party did not send GOP to D.C. to negotiate the terms of our surrender to socialism)
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To: metmom

Creationists have a huge advantage. We understand the competing theories and assumptions because we’ve been exposed to them all our lives, and have researched further than what we were spoon fed in humanist indoctrination centers.

I don’t think you’ll ever get over the hurdle with the poster in question. He’ll never get past his belief that adaptation is evolution.


45 posted on 12/04/2012 5:12:03 AM PST by MrB (The difference between a Humanist and a Satanist - the latter admits whom he's working for)
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To: Mr Ramsbotham
Yeah like the new super dupper flu shot seniors are being given this year vs what a younger person is given. Seems to affect more women than men....and there is NO HUMAN AT THE FDA BAD DRUG HOT LINE for those who are non computer users. Just hundreds of buttons to push. And you have to be your own detective and find out the info they should be finding.

Look at Lyrica it has a FIFTY PERCENT FAILURE rate due to bad side effects and yet they want to expand it's use to a 4th disease.

If you have side affects from a drug all your doctor does is switch you to a different one, and it does not get reported, doctors don't have time or financial resources to do so, nor does your drug store.

46 posted on 12/04/2012 6:11:25 AM PST by GailA (those who do not keep promises to Military, won't keep them to U)
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To: neverdem

Third leading cause of deaths in the USA, death by doctors

http://www.youtube.com/watch?v=8JF7TcPsmvI


47 posted on 12/04/2012 6:12:35 AM PST by GailA (those who do not keep promises to Military, won't keep them to U)
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To: allmendream
So your premise is that the antibiotic resistance existed before the antibiotic was invented?

And evolution explains it how?

An interesting, if idiotic, supposition. At least you are consistent!

By your own words you are condemned.

If antibiotic resistance were not somehow *programmed* in by evolution, then no bacteria would have survived to become antibiotic resistance.

So the creationist premise is that antibiotic resistance was programmed in by the Creator.

The evolutionary premise is that it just happened.

*It just happened*? How scientific is that?

48 posted on 12/04/2012 6:54:57 AM PST by metmom (For freedom Christ has set us free; stand firm therefore & do not submit again to a yoke of slavery)
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To: allmendream; GodGunsGuts; Fichori; tpanther; Gordon Greene; Ethan Clive Osgoode; betty boop; ...
So your premise is that the antibiotic resistance existed before the antibiotic was invented?

And evolution explains it how?

An interesting, if idiotic, supposition. At least you are consistent!

By your own words you are condemned.

If antibiotic resistance were not somehow *programmed* in by evolution, then no bacteria would have survived to become antibiotic resistance.

So the creationist premise is that antibiotic resistance was programmed in by the Creator.

The evolutionary premise is that it just happened.

*It just happened*? How scientific is that?

Let me guess, *Once upon a time a mutation occurred that would make bacteria be antibiotic resistant before antibiotics were invented, and so this mutation just hung around for millions to billions of years and meanwhile spread through the gene pool waiting in breathless anticipation for the day when mankind would invent antibiotics so it could express itself.*

49 posted on 12/04/2012 6:58:19 AM PST by metmom (For freedom Christ has set us free; stand firm therefore & do not submit again to a yoke of slavery)
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To: Mrs. Don-o; neverdem; Jim Robinson
Actually? I clicked once. Don’ know how that happened.

Wish Jim & Co. could add code to the site that checks every post against the user's previous post and stops it if it's an exact duplicate. Shouldn't be too intrusive of a check. Multi-posts seem to be a common malady.

50 posted on 12/04/2012 6:59:18 AM PST by TChris ("Hello", the politician lied.)
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