Posted on 09/11/2012 12:03:55 PM PDT by neverdem
Heart attack survivors using certain painkillers are more likely to die or suffer another event
People who have survived a heart attack seem to increase their risk of having another one, or of dying, by taking common painkillers called NSAIDs, a popular class of drugs that includes ibuprofen.
The unsettling link between non-steroidal anti-inflammatory drugs and heart attack risk is not new. The American Heart Association released guidelines in 2007 discouraging the use of any NSAIDs among people with a history of cardiovascular disease. Researchers in Denmark now bolster that link with the largest study to date of NSAID use in heart patients. The findings appear September 10 in Circulation.
In conducting the analysis, the scientists mined a huge database...
--snip--
Strand says the researchers have compiled “very impressive data.” But she notes that the researchers were unable to track use of aspirin, which is sold over the counter in Denmark. Daily low-dose aspirin limits heart attacks by reducing the blood’s clotting ability. “If you don’t take aspirin regularly, or if you take it simultaneously with NSAIDs, you lose that aspirin benefit,” Strand says. NSAIDs bind to the same molecular pocket on blood platelets as aspirin does, crowding out the aspirin. While NSAIDs have some ability to limit clotting caused by platelet aggregation, this capacity fades as the drugs wear off, she notes. In contrast, when aspirin binds to a platelet, its effect is irreversible, which is how daily aspirin suppresses stickiness in the population of platelets even as they are replenished.
“Some people think that if they are taking NSAIDs, they don’t need aspirin,” Strand says. “That’s absolutely wrong.” Patients who need NSAIDs for pain or inflammation, yet who have risk factors for heart disease, should take aspirin at least a few hours before taking an NSAID, she says...
(Excerpt) Read more at sciencenews.org ...
Is Naproxen an NSAID?
I remember Hank Williams. I remember he was drunk in the back seat of a car and that he choked to death on his own vomit. Too young to die, Hank was special.
Does anybody know anything AUTHORITATIVE about this?
We hear these days that just about everything out there can kill you...
Yes
I'm a licensed physician. I bolded those statements in the part of the story that I could post for a reason. It's what I know to be true for decades. I left other comments and links on the thread.
Thank you!
By the way... what are the risk factors for heart disease?
By the way... what are the risk factors for heart disease?
"The traditional risk factors for coronary artery disease are high LDL cholesterol, low HDL cholesterol, high blood pressure, family history, diabetes, smoking, being post-menopausal for women and being older than 45 for men, according to Fisher. Obesity may also be a risk factor."
Thanks.
That explains it perfectly.
But what about astaxanthin?
I don't know. Go to PubMed. Enter astaxanthin. Look at the left sidebar for review articles and click on it. I'd start there.
astaxanthin and inflammation gets 8 review atricles.
Look at the right sidebar: "4 free full-text articles in PubMed Central"
Thanks!!
Looks like I can keep taking it. I love this stuff..
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