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While I have a problem with big international pharma, big international chemical companies, and crony capitalism

You seem to have a problem with "big" companies which, at least to me, means you have a problem with success. I'm sure you also have a problem with "big" food, "big" oil, "big" insurance, "big" medical device, "big" transportation, "big" mining, "big" retail, "big" finance, "big" information and on and on.

The whole "big is bad" meme is a bunch of nonsense. If you have a problem with crony capitalism then your problem is with "big" government because government is the enabler of crony capitalism. Instead of railing on the private industries that created the massive amount of wealth we enjoy today, your ire should be directed at the big government that allows the quid pro quo to exist.

(think replacing CFC inhalers with garbage HFA ones

Again, your problem isn't with private industry. Do you think "big" bad pharma wanted to make the changes that will render their medicines less effective? Good grief. This is a result of government overreach. Period.

I am also aware of the cost of developing new medications and manufacturing quality generics.

If true, how in the heck can you complain about "big" pharma and your alleged crony capitalism? It costs hundreds of millions of dollars and more than a decade in time to bring a NME to market. The FDA kills most of these new offerings before they even reach the clinical trial stage. Yet, you want us to believe that "big" pharma and the fedgov are joined at the hip helping each other out. What a pantload.

... You seem to have a problem with "big" companies which, at least to me, means you have a problem with success. ...
If you have a problem with crony capitalism then your problem is with "big" government because government is the enabler of crony capitalism. ...
The FDA kills most of these new offerings before they even reach the clinical trial stage. Yet, you want us to believe that "big" pharma and the fedgov are joined at the hip helping each other out. ...

Maybe that's what it means in your mind, but I notice you ignored the possibility that only 'big' companies have the resources to indulge in crony capitalism and deter competition from new and small companies. We live in an age of profit "uber alles", an age in which the only obligation companies have is to earn profit for their stock holders.

To deny that there are those out there who place money and profit above all other things is to deny reality. There is a dark side to human nature that Bastiat in The Law refered to as the ‘common tendency’ of ‘mankind’ ‘when they can’ to ‘live and prosper at the expense of others’.

Big pharma wouldn't use lobbyists on K street to pass on campaign contributions to buy favors now would they?
The FDA didn't violate its own regulations to speed all those new inferior HFA inhalers to market when there already was a medical exception to the Montreal Protocol did they?
Dupont didn't join up with the greenies on the theory that chloroflourcarbons cause the ozone hole because their patent on an efficient process for producing chloroflourcarbons did they?
Big pharma didn't bribe and subsidize:
The American Lung Association (ALA)
The Asthma and Allergy Foundation of America (AAFA)
The Allergy and Asthma Network Mothers of Asthmatics (AANMA)
The American Academy of Allergy, Asthma and Immunology (AAAAI)
The American Academy of Pediatrics
The American Association for Respiratory Care (AARC)
The American College of Allergy, Asthma and Immunology (ACAAI)
The American College of Chest Physicians (ACCP)
The American Thoracic Society (ATS)
to 'educate' consumers on how to use the new HFA inhalers did they?
The FDA didnt' have the gall to tell consumers of asthma inhalers, i.e. people have difficulty breathing, that "It is important to remember that it is the deep breath that you take with each puff that gets the medication into your lungs, not the force of the spray." did they?