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Arsenic Linked to Diabetes
WebMD Health News ^ | Aug. 19, 2008 | Caroline Wilbert

Posted on 08/20/2008 7:53:21 PM PDT by neverdem

Reviewed By Elizabeth Klodas, MD, FACC

13 Million Americans Are Exposed to Dangerous Levels of Arsenic Through Drinking Water

Exposure to arsenic, typically through drinking water, is linked to diabetes, according a study published in the Journal of the American Medical Association.

Thirteen million Americans — and millions more worldwide — are exposed to drinking water contaminated with more inorganic arsenic than the Environmental Protection Agency has deemed safe. The EPA standard is 10 micrograms per liter.

Researchers, led by Ana Navas-Acien, MD, PhD, of the Johns Hopkins Bloomberg School of Health, studied 788 adults who had their urine tested for arsenic exposure in the 2003-2004 National Health and Nutrition Examination Survey. Participants with type 2 diabetes had a 26% higher level of total arsenic in their urine than those without the disease. Levels of organic arsenic, called arsenobetaine, which is often found in seafood, were similar between two groups. Arsenobetaine is considered nontoxic.

After adjusting for diabetes risk factors and seafood intake, researchers found that participants in the top one-fifth of total urine arsenic levels (16.5 micrograms per liter) had 3.6 times the odds of having type 2 diabetes as those in the lowest one-fifth (3 micrograms per liter).

Researchers also looked at levels of dimethylarsinate, a compound created when inorganic arsenic is metabolized before excretion. Participants in the top one-fifth of urine dimethylarsinate levels (6 micrograms per liter) had 1.6 times the odds of having type 2 diabetes as those in the lowest one-fifth (2 micrograms per liter.)

There are several reasons that inorganic arsenic may contribute to diabetes. Insulin-sensitive cells that are exposed to insulin and sodium arsenic appear to take in less glucose than cells exposed only to insulin. Arsenic could influence genetic factors that interfere with insulin sensitivity and other processes. Arsenic also may contribute to oxygen-related cell damage, inflammation, and cell death, all of which are linked to diabetes.

The study adds more evidence that inorganic arsenic in drinking water is dangerous. Previous research has linked arsenic to cancer and other health problems.

"Given widespread exposure to inorganic arsenic from drinking water worldwide, elucidating the contribution of arsenic to the diabetes epidemic is a public health research priority with potential implications for the prevention and control of diabetes," the authors conclude.

An accompanying editorial written by Molly L. Kile, ScD, and David Christiani, MD, MPH, both of the Harvard School of Health, highlights the increasing prevalence of type 2 diabetes, which affects 7.8% of Americans (24 million individuals). Most research focus has been on prevention through medication and lifestyle changes, but additional research needs to be done on environmental factors, the authors write.

In the meantime, Kile and Christiani write, "It is prudent to minimize arsenic exposures while its effect on metabolic diseases continues to be researched."

SOURCES: Navas-Acien, A., TheJournal of the American Medical Association, Aug. 20, 2008; vol 300. Kile, M., Christiani, D., The Journal of the American Medical Association, Aug. 20, 2008; vol 300. News release, The Journal of the American Medical Association.

©2008


TOPICS: Culture/Society; News/Current Events; Testing
KEYWORDS: arsenic; diabetes; environment; fallofrome; godsgravesglyphs; health; medicine; t1; type2; water
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Arsenic Exposure and Prevalence of Type 2 Diabetes in US Adults
1 posted on 08/20/2008 7:53:21 PM PDT by neverdem
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To: austinmark; FreedomCalls; IslandJeff; JRochelle; MarMema; Txsleuth; Newtoidaho; texas booster; ...
FReepmail me if you want on or off the diabetes ping list.
2 posted on 08/20/2008 7:56:00 PM PDT by neverdem (I'm praying for a Divine Intervention.)
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To: neverdem
Still not enough evidence to pin point the cause. Why some get diabetes and other don't in the same family.
3 posted on 08/20/2008 7:56:28 PM PDT by Orange1998
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To: neverdem
Wasn't the extremely low EPA restriction on arsenic one of BJ Clinton's 11th hour gifts?
4 posted on 08/20/2008 7:57:26 PM PDT by Grizzled Bear ("Does not play well with others.")
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To: neverdem
Ummm. As a professional culinarian, graduate of culinary school and everything.... With a background in engineering, and a clue about genetics and chemistry. As a man that believes in living simply from God's bounteous resources, and eating a little bit of damn near everything.....

LAY OFF THE PROCESSED CARBS!

That is all. (White bread is poison)

/johnny

5 posted on 08/20/2008 7:59:12 PM PDT by JRandomFreeper (Bless us all, each, and every one.)
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To: neverdem
The (Ph.D) diabetic I know points to excessive carbohydrate intake as the cause of her condition.

And, as she as radically controlled her carb consumption, her blood sugar readings have normalized (and she's lost over 70 lbs).

6 posted on 08/20/2008 7:59:54 PM PDT by Seaplaner (Never give in. Never give in. Never...except to convictions of honour and good sense. W. Churchill)
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To: neverdem
I have type 2 and I drink much more water a day.
7 posted on 08/20/2008 8:03:31 PM PDT by HuntsvilleTxVeteran (Remember the Alamo, Goliad and WACO, It is Time for a new San Jacinto!)
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To: HuntsvilleTxVeteran

Do you get your water through a filter? Like a PUR filter or a reverse-osmosis filter? They usually take out arsenic.

While it may be true that there is a relationship between arsenic and type 2 diabetes, the whole refined carbs/sugars issue is a much bigger one than the arsenic, I believe.


8 posted on 08/20/2008 8:07:37 PM PDT by Secret Agent Man (I'd like to tell you, but then I'd have to kill you.)
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To: JRandomFreeper
Actually wheat in any form (processed or otherwise) really is POISON to anyone with the gene for Celiac, or any one of 8 other recently discovered analogous genes that create Cealiac-like symptoms.

Celiac is far more serious than Type II diabetes.

At the same time, having one or the other is often associated with the other. That is, you can have the gene for Celiac or similar condition AND an increased probability of having Type II, or Type I diabetes.

If you have both the odds are good you have a porphyria or two which is mediated through the action of a gene ordinarily used to construct heme. There are, currently, 83 known variants of this same gene.

I suspect this arose during a period when folks in the far North ate a lot of seal. Those critters have 25 times as much iron in their tissues as the next highest ranking animal (the reindeer).

You could be short the gene for "blue" retinal cones, have extra copies of the gene for "red" retinal cones, and a square shaped heart with extra large atrial chambers (which is kind of like having an extra heart in cold weather because it allows you to reduce your airflow while enhancing your ability to gather oxygen from the air sacs in your lungs).

Taken all together, it's rather far fetched to even begin to think that higher than healthy background arsenic levels have anything to do with many cases of Type II diabetes.

9 posted on 08/20/2008 8:08:51 PM PDT by muawiyah
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To: neverdem

Wait a minute - arsenic is dangerous?


10 posted on 08/20/2008 8:08:53 PM PDT by Mentos
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To: Seaplaner

Many years ago I read that the nation with the highest rate of type II diabetes was Kuwait. Type II diabetes is a lifestyle issue (not that lifestyle is a guaranteed cure after it manifests itself).


11 posted on 08/20/2008 8:08:55 PM PDT by The Duke (I have met the enemy, and he is named 'Apathy'!)
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To: Seaplaner

I just decided that I would change the way I eat after watching “You are what you eat” on the BBC...I have cut out almost all processed carbs...except whole wheat bread...which I eat in moderation...lots of veggies and some fruit...a little meat now and than but I don’t go overboard and some dairy. I eat veggies until I am full..and in little over 2 months I have lost 31 lbs. I have a lot more energy...even getting back on my bike and taking a spin or two around town. I feel great, my thinking is clearer...and for some reason that nagging craving for sweets has disappeared. I was afraid of developing diabetes because of my weight...my son in law has it and just went through a horrendous time with cellulitis...the doctors had to remove a good portion of his belly because it was dead. He almost died from it.

Looking at what I ate and changing my thinking about food is probably the best decision I have ever made.


12 posted on 08/20/2008 8:11:16 PM PDT by leenie312 (learly and effectively)
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To: Orange1998; neverdem
Still not enough evidence to pin point the cause. Why some get diabetes and other don't in the same family.

(Note - I didn't spend 15 bucks to read the JAMA article, and science reporting is notoriously uneven, so maybe the underlying JAMA article is not snark-worthy).

I wonder if they thought of the possibility that having diabetes could render your body less capable of excreting arsenic.

I guess avoiding that whole issue of deciding cause and effect makes fear-mongering so much easier, and certainly makes it easier to call for "prudent" restrictions. /sarc

13 posted on 08/20/2008 8:12:31 PM PDT by slowhandluke (It's hard work to be cynical enough in this age)
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To: HuntsvilleTxVeteran

My type 2 diabetes was not the result of overeating, or a genetic disposition, or consuming a boatload of carbs.

Thanks to the government (from whom too many ignorant people want their healthcare), my diabetes is the result of Agent Orange exposure in ‘Nam. It’s only ONE symptom of Agent Orange exposure . . . . . . . along with ALS (Lou Gehrig’s disease), cystic fibrosis, fibromyalgia, muscular dystrophy and a host of other delightful diseases.

Despite many “wise and knowledgeable folks who make stqatements about overeating and obesity, those aren’t the only ways people get Type II Diabetes.

Sometimes, the government REALLY is . . . “here to HELP you!”

/sarc (last line only)


14 posted on 08/20/2008 8:13:21 PM PDT by DustyMoment (FloriDUH - proud inventors of pregnant/hanging chads and judicide!!)
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To: JRandomFreeper

Yes, but (soft) white bread with French butter is so GOOOOOOD. (Heidi’s Grandmother was right).


15 posted on 08/20/2008 8:18:18 PM PDT by bboop (Stealth Tutor)
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To: neverdem

Sounds like BS to me.

Im sure it doesnt have a thing to do with all the sodas and sugar people are pumping through their systems


16 posted on 08/20/2008 8:18:48 PM PDT by mylife (The Roar Of the Masses Could Be Farts)
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To: muawiyah
Someone with a clue.

Amazing.

Males with colorblindness actually are color-shifted to infra-red. Not much, but enough. But I don't have to write a paper to justify a great big grant for it.

So it doesn't count.

My advice remains the same. Eat whatever is in season, and isn't too easy to catch.

In Central NW Texas, that would be italian and mexican poverty foods. Beans, corn, 'maters, onions. Cheese. Lots of cheese. And goats and squirrel.

/johnny

17 posted on 08/20/2008 8:21:08 PM PDT by JRandomFreeper (Bless us all, each, and every one.)
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To: Orange1998
Why some get diabetes and other don't in the same family.

Targeting epigenetic pathways in obesity and diabetes

18 posted on 08/20/2008 8:27:51 PM PDT by neverdem (I'm praying for a Divine Intervention.)
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To: Grizzled Bear
Wasn't the extremely low EPA restriction on arsenic one of BJ Clinton's 11th hour gifts?

IIRC, yes.

19 posted on 08/20/2008 8:30:19 PM PDT by neverdem (I'm praying for a Divine Intervention.)
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To: slowhandluke

I was thinking the same, so many cause and effects left unanswered.


20 posted on 08/20/2008 8:30:23 PM PDT by Orange1998
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To: bboop
I hear you. I have the "@itch" in the refrigerator. She's the 180 grams of leavened loaf that I pass from loaf to loaf in the traditional 1400s french pre-ferment style.

Yes, it is good. And I'm qualified to bake in a bunch of institutions, all over the world. But I don't make bread much.

And never simple white bread.

Sourdough only, or at least pre-ferment, some token rye.

But it IS good. And I have creme fraise in the box, along with a little bit of seasoned goat cheese.

No! covers a lot of answers around here right now.

I may sneak some chevre on crackers with roasted garlic later..... ;)

/johnny

21 posted on 08/20/2008 8:31:44 PM PDT by JRandomFreeper (Bless us all, each, and every one.)
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To: All

anyone, did they develop an inhalant for treatment of diabetes. If so, what happened?


22 posted on 08/20/2008 8:32:31 PM PDT by purpleraine
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To: Grizzled Bear
Yes, Clinton reduced the permitted level of arsenic just before leaving office (but I think it wouldn't take effect for a while). Bush initially reversed it but I think eventually went along with the new rules...but meanwhile allowed the 'Rats to bombard the public with the message that he didn't care if America's kids were poisoned with arsenic.

The Fox News website has a link to a video from Shepard Smith's program on Wed., where he discusses the story with a doctor, who quotes the price of $3500 for the kind of water purifier you'd need for your house to be safe.

23 posted on 08/20/2008 8:34:05 PM PDT by Verginius Rufus
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To: DustyMoment

FWIW :

http://rds.yahoo.com/_ylt=A0geu7kx36xIXqAAgGJXNyoA;_ylu=X3oDMTEyZGhtNHZ1BHNlYwNzcgRwb3MDMQRjb2xvA2FjMgR2dGlkA0gxNDRfNzg-/SIG=11r7o83g3/EXP=1219375281/**http%3a//en.wikipedia.org/wiki/Agent_Blue

http://rds.yahoo.com/_ylt=A0geu7kx36xIXqAAjmJXNyoA;_ylu=X3oDMTEyYm82OGo3BHNlYwNzcgRwb3MDOARjb2xvA2FjMgR2dGlkA0gxNDRfNzg-/SIG=11q5ieh74/EXP=1219375281/**http%3a//bluewaternavy.org/updatelog.htm

http://rds.yahoo.com/_ylt=A0geu71T4KxIYnwA15JXNyoA;_ylu=X3oDMTEyZGhtNHZ1BHNlYwNzcgRwb3MDMQRjb2xvA2FjMgR2dGlkA0gxNDRfNzg-/SIG=11t6fteom/EXP=1219375571/**http%3a//en.wikipedia.org/wiki/Agent_Orange

Welcome Home...


24 posted on 08/20/2008 8:34:53 PM PDT by 1COUNTER-MORTER-68 (THROWING ANOTHER BULLET-RIDDLED TV IN THE PILE OUT BACK~~~~~)
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To: HuntsvilleTxVeteran
I have type 2 and I drink much more water a day.

That's a symptom of diabetes called polydipsia. How well is your blood sugar controlled?

25 posted on 08/20/2008 8:36:08 PM PDT by neverdem (I'm praying for a Divine Intervention.)
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To: neverdem

I prefer my Arsenic with “Elderberry Wine” thank you...


26 posted on 08/20/2008 8:36:24 PM PDT by Clemenza (No Comment)
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To: Mentos
arsenic is dangerous?

It's fairly safe used topically, if you are near New Orleans. And it does get rid of the creepy crawlies.

Your mileage may vary.

I am not a government scientist.

/johnny

27 posted on 08/20/2008 8:39:16 PM PDT by JRandomFreeper (Bless us all, each, and every one.)
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To: neverdem; All

Thanks for posting and thanks to every poster on this thread sharing personal experiences/information/links.

Health/life BUMP!


28 posted on 08/20/2008 8:42:51 PM PDT by PGalt
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To: Clemenza
I prefer my Arsenic with “Elderberry Wine” thank you...

D.A.: "When you poisoned your husband, did you ever feel any misgivings about what your were doing"?

Witness: "Only after he tasted it, understood what it was, and asked for seconds.... I felt a little sad then, but he seemed so happy."

/johnny

29 posted on 08/20/2008 8:49:30 PM PDT by JRandomFreeper (Bless us all, each, and every one.)
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To: neverdem

Waitasec. Just today I was reading how Type 1 diabetes may actually be an evolutionary adaptation for cold weather:

http://cat.inist.fr/?aModele=afficheN&cpsidt=16791319

That is, the higher blood levels of some of the chemicals associated with diabetes act like antifreeze.

Importantly, for every white American, 1.6 black Americans suffers from diabetes. The actual figures for black Americans may be even higher, because there is a serious shortfall in diabetes diagnosis for black Americans:

http://www.blackhealthcare.com/BHC/Diabetes/Description.asp

But that sort of goes against the “antifreeze” theory.

And here’s another twist: Geologically, North America is a young continent. Its topsoil is full of salts and metals. Europe is also young, and so people with European origins living in America tend to be far less sensitive to salts and metals.

However, geologically Africa is a very old continent, and most of the salts and metals have been leached out of its topsoil. For this reason, people with African ancestry are much more sensitive to salts and metals and their effects.

For example, it is known both that black children are more susceptible to injury from the intake of metallic lead than non black children, though it is generally bad for all. Black Americans also have a much higher rate of high blood pressure, likely associated with a lower tolerance for salts.

However, across the US, with its high amounts of salts and metals, the *types* of salts and metal varies considerably. In some areas, water wells cannot be drilled because of sky high arsenic in the ground water. Other places have very little indeed. But this is not limited to arsenic. It is true also of lead, cadmium (which is very toxic), mercury, uranium, chromium, thallium, antimony, copper, nickel, and selenium.

Right now, an entire city in Oklahoma has been condemned because it used to host a lead mine. People don’t have to leave, but nobody new is allowed to move in.


30 posted on 08/20/2008 8:55:03 PM PDT by yefragetuwrabrumuy
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To: Grizzled Bear; Verginius Rufus

Arsenic Levels in Water: A Clinton Trap

http://www.aim.org/media-monitor/arsenic-levels-in-water-a-clinton-trap/


31 posted on 08/20/2008 9:01:18 PM PDT by preacher (A government which robs from Peter to pay Paul will always have the support of Paul.)
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To: yefragetuwrabrumuy
and most of the salts and metals have been leached out of its topsoil.

I would need a cite for that, because I don't believe it. The more you turn over a soil, the more crap you turn up. That's observation over the years.

/johnny

32 posted on 08/20/2008 9:01:18 PM PDT by JRandomFreeper (Bless us all, each, and every one.)
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To: JRandomFreeper

Arsenic is found in magmatic rocks and leach out naturally.

You can get filters for it. No big deal.

However, arsenic would explain why so many Democrats are brain-damaged.


33 posted on 08/20/2008 9:10:15 PM PDT by MadMax, the Grinning Reaper
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To: leenie312
I have lost 31 lbs. I have a lot more energy...even getting back on my bike and taking a spin or two around town. I feel great, my thinking is clearer...and for some reason that nagging craving for sweets has disappeared.

Leenie, what a great story you have!

Good on you (and keep the "mo").

34 posted on 08/20/2008 9:16:12 PM PDT by Seaplaner (Never give in. Never give in. Never...except to convictions of honour and good sense. W. Churchill)
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To: JRandomFreeper

I have a $itch that goes on 50% off twice a year and her name is Godiva.


35 posted on 08/20/2008 9:39:30 PM PDT by Global2010 (OKIE DOKIE)
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To: JRandomFreeper

We are talking some serious years here.

North America was formed during the Phanerozoic Era, within 545 million years ago. We are still in that era.

Africa was formed during the Neoproterozoic Era 542-1000+ million years. It didn’t stop forming until we had just begun forming.

And there are limits to how much “stuff” you can turn up in topsoil before the topsoil is gone, washed or blown away, and new topsoil is formed. Salts and metals may exist down deep, but the substantial quantities concentrated near the surface are gone.


36 posted on 08/20/2008 9:53:56 PM PDT by yefragetuwrabrumuy
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To: neverdem
My brother in law joined us at my son's graduation from the University of Phoenix. Afterward, we went to lunch. He seemed to have an insatiable thirst. My wife and I both suspected diabetes. He went to the doctor...bingo! Diabetes. He's getting it treated now. He had no idea that his thirst was a possible sign of diabetes.
37 posted on 08/20/2008 11:05:44 PM PDT by Myrddin
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To: El Gato; Ernest_at_the_Beach; Robert A. Cook, PE; lepton; LadyDoc; jb6; tiamat; PGalt; Dianna; ...
Senator Barak Obama Has A Head Tilt (Medical Implications)

New method of growing human embryonic stem cells may revolutionise Parkinson's therapy

Scared Senseless (book review)

New Way to Kill Viruses: Shake Them to Death

FReepmail me if you want on or off my health and science ping list.

38 posted on 08/20/2008 11:32:12 PM PDT by neverdem (I'm praying for a Divine Intervention.)
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To: Myrddin

Before getting diabetes, my thirst was insatiable. Always was and everyone always asked if I was checked for diabetes. During routine physicals, the blood sugar was always perfect.

Then, even though I do not take any meds for it and have only made slight modifications to my diet, my thirst is dramatically less.

This seems to be the opposite of what you just cited. Strange disease, huh?


39 posted on 08/20/2008 11:47:49 PM PDT by Harvey105
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To: StayAt HomeMother; Ernest_at_the_Beach; 1ofmanyfree; 21twelve; 24Karet; 2ndDivisionVet; 31R1O; ...

· join list or digest · view topics · view or post blog · bookmark · post a topic ·

 
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I'm reminded of that myth about how the fall of Rome could be attributed to lead pipes. Thanks neverdem.

To all -- please ping me to other topics which are appropriate for the GGG list.
GGG managers are SunkenCiv, StayAt HomeMother, and Ernest_at_the_Beach
 

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40 posted on 08/21/2008 12:04:09 AM PDT by SunkenCiv (https://secure.freerepublic.com/donate/_______Profile hasn't been updated since Friday, May 30, 2008)
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To: Clemenza
I prefer my Arsenic with “Elderberry Wine” thank you...

Elderberry extract is touted as a treatment for influenza, Clemenza. Is there a term for that besides rhyming?

Anyway, it's sold in drug stores. The Israeli's did some studies on it, IIRC. The trade name escapes me.

41 posted on 08/21/2008 12:39:07 AM PDT by neverdem (I'm praying for a Divine Intervention.)
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To: Myrddin

I never got an answer about the Texan’s blood glucose control.


42 posted on 08/21/2008 12:42:32 AM PDT by neverdem (I'm praying for a Divine Intervention.)
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To: JRandomFreeper

Nothing erases a mistake/stray dust in a pastel painting as well as a soft blob of fresh white bread.

It also does a great job of picking up tiny broken glass splinters, if you have broken a light bulb, for example.

So, it’s not *totally* worthless......;]


43 posted on 08/21/2008 2:41:01 AM PDT by Salamander (And don't forget my Dog; fixed and consequent......)
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To: theKid51; Apple Blossom

ping


44 posted on 08/21/2008 2:52:44 AM PDT by bmwcyle (If God wanted us to be Socialist, Karl Marx would have been born in America.)
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To: JRandomFreeper
My husband has type II diabetes and here we thought it was because both of his parents, all four of his grandparents and all his ancestors as far back as we can discover had it. Now I discover it was all that whitebread they ate.
45 posted on 08/21/2008 5:08:30 AM PDT by Ditter
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To: JRandomFreeper

Amen!


46 posted on 08/21/2008 5:16:00 AM PDT by coop71 (Being a redhead means never having to say you're sorry...)
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To: JRandomFreeper

LOL! That’s awful. :)


47 posted on 08/21/2008 6:01:42 AM PDT by trisham (Zen is not easy. It takes effort to attain nothingness. And then what do you have? Bupkis.)
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To: nnn0jeh

ping


48 posted on 08/21/2008 7:58:58 AM PDT by kalee
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To: muawiyah

Are you familiar with Hereditary Hemachromatosis (the (the overbinding of iron)? Its kind of the reverse of what you just explained... common in Northern Europeans...genetically my ancestors adapted to the harsh growing conditions by overstoring the minute amounts they were exposed to given their almost constant diet of root vegetables.

In today’s world, w/iron fortifying mosts processed foods, the storage of excess iron leads to diabetes, cancers, athritis, heart problems’ etc.

To anyone reading this, if you are of Irish, English, or Welsh ancestry, have your doctor order the simple blood test to screen for HH. It is very a very common genetic disorder...yet not often screened for.


49 posted on 08/21/2008 8:10:43 AM PDT by PennsylvaniaMom (I am still bitter.)
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To: neverdem
Elderberry extract is touted as a treatment for influenza, Clemenza. Is there a term for that besides rhyming?

Anyway, it's sold in drug stores. The Israeli's did some studies on it, IIRC. The trade name escapes me.

Great stuff, works every time! Sambucol

50 posted on 08/21/2008 8:43:02 AM PDT by muggs (No matter who wins, America loses)
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