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Scientists Find Cancer Culprits in Cigarette Smoke
Health Day Via Yahoo! ^ | 2-29-08

Posted on 02/28/2008 4:16:42 PM PST by Dysart

HURSDAY, Feb. 28 (HealthDay News) -- It's long been known that smoking causes lung cancer, but a new study is the first to show that the hydrogen peroxide in cigarette smoke is what actually causes healthy lung cells to turn cancerous.

Researchers from the University of California, Davis, said their findings may help lead to new treatments for lung cancer and may help the tobacco industry develop "safer" cigarettes by eliminating such substances in the smoke.

"With the five-year survival rate for people with lung cancer at a dismally low 15.5 percent, we hope this study will provide better insight into the identification of new therapeutic targets," senior author Tzipora Goldkorn said in a prepared statement.

In this laboratory study, the researchers exposed different sets of human lung cells to cigarette smoke or hydrogen peroxide and then incubated the cells for one to two days. The cells were then compared to unexposed airway cells. The cells exposed to cigarette smoke and those exposed to hydrogen peroxide showed the same molecular signatures of cancer development. The unexposed cells showed no such changes.

The findings are published in the March issue of The FASEB Journal, published by the Federation of American Societies for Experimental Biology.

Guns kill, bombs kill and cigarettes kill," Dr. Gerald Weissmann, editor-in-chief of The FASEB Journal, said in a prepared statement. "While biologists can't do much about the first two, studies like this will help in the fight against tobacco-related death and disease. These experiments not only pinpoint new molecular targets for cancer treatment, but also identify culprits in cigarette smoke that eventually will do the smoker in."

Cigarette smoking, which causes more than 400,000 deaths a year in the United States (about one in five of all deaths) is the leading preventable cause of premature death in the country, according to the U.S. Centers for Disease Control and Prevention. Smoking causes 90 percent of all lung cancer deaths in men and about 80 percent of lung cancer deaths in women.

Tobacco smoke contains more than 4,000 chemical compounds, including 43 that are know to cause cancer, according to a U.S. Surgeon General report released in 2000.


TOPICS: News/Current Events
KEYWORDS: cancer; cigs

1 posted on 02/28/2008 4:16:53 PM PST by Dysart
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To: Dysart

We have consensus!


2 posted on 02/28/2008 4:18:05 PM PST by Izzy Dunne (Hello, I'm a TAGLINE virus. Please help me spread by copying me into YOUR tag line.)
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To: Dysart

I thought it was the benz-alpha-pyrene and methyl chrysene, who knew?

And then there was the polonium theory, and the “tar” and nicotine...


3 posted on 02/28/2008 4:19:42 PM PST by DBrow
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To: Dysart
It's long been known that smoking causes lung cancer, but a new study is the first to show that the hydrogen peroxide in cigarette smoke is what actually causes healthy lung cells to turn cancerous.

I'm sure there are a lot of very nervous blondes in the nation tonight.

4 posted on 02/28/2008 4:22:06 PM PST by Dahoser (America's great untapped alternative energy source: The Founding Fathers spinning in their graves.)
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To: Dysart
This is soooooooo true IMHO, today is my 4 month quit date, the Nicotine was a breeze it’s all the other crap, hell I had a Ammonia fit for weeks.
5 posted on 02/28/2008 4:22:26 PM PST by cmsgop ( You go to da box..... you feel shame)
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To: Dysart
OoooooooooooKay ... what about all those H2O2-based mouth products? Seems minute traces might find their way down the airway. Cumulative damage? How long until we hear the lawyer's TV ads asking if we ever used a peroxide-based oral product?
6 posted on 02/28/2008 4:22:31 PM PST by NonValueAdded (Who Would Montgomery Brewster Choose?)
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To: Dysart

Is the hydrogen peroxide produced in the burning process?


7 posted on 02/28/2008 4:24:21 PM PST by Rb ver. 2.0 (Global warming is the new Marxism.)
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To: DBrow

Well, Nicotine does speed tumor growth, no doubt. But these are in growths already established.


8 posted on 02/28/2008 4:24:38 PM PST by Dysart
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To: Dysart
Hydrogen Peroxide? That's it ? Why ...just oxidize it to pure harmless water vapor and smoke to your heart's content !

Sigh.. wonder what these 'researchers' will find next to contradict this finding.

9 posted on 02/28/2008 4:24:45 PM PST by libh8er
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To: Dysart

Take it out and give the cigarettes back at a reasonable price.


10 posted on 02/28/2008 4:25:47 PM PST by donna (If America is not a Christian nation, it will be part of the Islamic nation. Take your pick.)
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To: cmsgop
today is my 4 month quit date

Congrats. I'm at 7 months. I admit, though, my first thought when reading this was, "Take out the hydrogen peroxide and let me smoke my cigarettes again".

11 posted on 02/28/2008 4:32:00 PM PST by tnlibertarian
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To: Rb ver. 2.0; y'all
Is the hydrogen peroxide produced in the burning process?

Yes. And maybe someone more familiar with the process involving cig smoke condensation which activates HP can explain it.(Hes says hopefully) Can't imagine the formaldehyde is esp healthful either.

12 posted on 02/28/2008 4:32:46 PM PST by Dysart
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To: Dysart

Guns, without a human agent, do not kill. Most bombs, without a human agent, do not kill (there are a few unstable bombs that do detonate “on their own,” but it was a human that created that instability).


13 posted on 02/28/2008 4:33:23 PM PST by ought-six
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To: donna

“Take it out and give the cigarettes back at a reasonable price.”

Lung cancer is just one of many diseases that cigarettes cause. Cigarettes should have no place in a healthy society just like cocaine, meth, and other agents of death. With at least cocaine and meth, you can say they legally sold for profit.


14 posted on 02/28/2008 4:34:05 PM PST by sagar
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To: Dysart

Hydrogen peroxide is nothing but water with an extra O, but I guess if they can declare ozone a terrible polluntant, they can call hydrogen peroxide a carcinogen.


15 posted on 02/28/2008 4:40:17 PM PST by Eva (Benedict Arnold was a war hero, too.)
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To: sagar
With at least cocaine and meth, you can say they legally sold for profit.

Huh?

Are you high?

16 posted on 02/28/2008 4:49:58 PM PST by Wingy
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To: Dysart

And if it turns out that the hydrogen peroxide is not present in second hand smoke ... or is significantly reduced in content by the time it gets to someone else’s nose ... then we can make a stronger case against second hand smoke being a cancer causing agent.


17 posted on 02/28/2008 4:58:12 PM PST by who_would_fardels_bear
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To: sagar
"Cigarettes should have no place in a healthy society just like cocaine, meth, and other agents of death."

If you don't like such things then don't do them. Leave the state out of it please.

18 posted on 02/28/2008 4:58:33 PM PST by KoRn (CTHULHU '08 - I won't settle for a lesser evil any longer!)
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To: sagar
Cigarettes should have no place in a healthy society just like cocaine, meth, and other agents of death.

So where does Freedom fall into your little healthy Scenerio ? while your telling us what we should be allowed to have in a healthy society what would you propose to do with those who wish to be free to do as they please healthy or no ?

Not meant to be a flame i'm just curious ....

19 posted on 02/28/2008 5:09:43 PM PST by ATOMIC_PUNK (Drink no longer water, but use a little wine for thy stomach's sake and thine often infirmities.)
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To: sagar

They are not intoxicating so it’s no one’s business.

Fat people are more expensive.


20 posted on 02/28/2008 5:12:22 PM PST by donna (If America is not a Christian nation, it will be part of the Islamic nation. Take your pick.)
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To: tnlibertarian
LOL!!!!! Yup, I totally agree!
21 posted on 02/28/2008 5:14:00 PM PST by cmsgop ( You go to da box..... you feel shame)
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To: who_would_fardels_bear

And if it turns out that the hydrogen peroxide is not present in second hand smoke ... or is significantly reduced in content by the time it gets to someone else’s nose ... then we can make a stronger case against second hand smoke being a cancer causing agent.
***************************************************
You can count on it Hydrogen Peroxide is a strong oxidizer ,, thats how it disinfects ,, same as good old ozone is an oxidizer.. they are unstable and react with the first thing they touch and are no more...


22 posted on 02/28/2008 5:22:27 PM PST by Neidermeyer
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To: sagar
Lung cancer is just one of many diseases that cigarettes cause. Cigarettes should have no place in a healthy society just like cocaine, meth, and other agents of death. With at least cocaine and meth, you can say they legally sold for profit.

So glad you did not say alcohol :-)

23 posted on 02/28/2008 5:30:53 PM PST by MrPiper
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To: Dysart
Hydrogen peroxide

Hmmmm, isn't this what the dentist said to rinse my mouth out with after oral surgery?

24 posted on 02/28/2008 5:32:58 PM PST by MrPiper
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To: MrPiper
It's always been considered harmless unless taken internally. I've been told to gargle with it too but have always been leery of something that was just dandy sloshing around my mouth but could be harmful or fatal if swallowed. Just never cared for the idea of it.
25 posted on 02/28/2008 5:40:02 PM PST by Dysart
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To: donna
Fat people are more expensive.

But we're worth it!

26 posted on 02/28/2008 5:45:38 PM PST by null and void (When you vote, remember your wallet, the welfare recipients do...)
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To: Wingy

I think sagar a word out.


27 posted on 02/28/2008 7:14:26 PM PST by Erasmus (Exile from Gondwanaland)
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To: cmsgop

"..... today is my 4 month quit date,...."

WONDERFUL! Congratulations on your resolve, keep up the good work! My husband quit a year ago September after many, many years of smoking.

28 posted on 02/29/2008 6:03:03 AM PST by Mila
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To: Mila
Thank You Mila, I used to know a girl named Mila along time ago,ever live in Virgina?, LOL!
29 posted on 02/29/2008 12:51:52 PM PST by cmsgop ( You go to da box..... you feel shame)
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To: cmsgop

".... I used to know a girl named Mila along time ago,ever live in Virgina?"

No sorry :), I've never had the pleasure of living or visiting in Virginia.

30 posted on 03/01/2008 2:20:09 AM PST by Mila
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To: Wingy; KoRn; ATOMIC_PUNK; donna

Sorry for the late response. Here it goes.

“Responsible” consumers should be able to purchase cocaine and meth; free market should determine their price and distribution. Why is the government involved in restricting free market for stimulants such as cocaine and methamphetamine? I thought America was a free country where entrepreneurs should be able to produce and sell anything to the market.

I am being sarcastic, but my point is a valid one. If cigs cause all kinds of cancers and ailments (#1 cause of preventable death), then why are they even allowed and protected as consumer good?

Nicotine addiction caused by cigs is very hard to break; addicts can NOT act “responsibly” if their brain chemistry and nicotine receptors tell them to pump toxic fumes down their esophagus. Ask any smoker if they can “choose” not to smoke — they go crazy for a few weeks and most of them revert back to being slaves to the fumes.

Besides, it is a terrible price to pay for own health, and financial burden to themselves and NON SMOKERS who have to pay higher amount than needed to cover the addicts who “decide” to smoke every 2 hours to maintain their nicotine levels.

It isn’t about freedom. It is slavery.


31 posted on 03/02/2008 6:26:21 PM PST by sagar
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