Alcohol's Benefits Extend to Hypertension

I would disagree in that it seems that a lot dope smokers become lazy and shabby.

I would think they don't have anything to generate any motivation in their life, or they were just lazy slobs in the first place.

Thank's for the link on FNC's update. You jogged my memory. Here for your perusal are the results of a search on PubMed using (Alzheimers's OR Parkinson's) AND nicotine:

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Items 1-20 of 383

of 20

1:	Newhouse PA, Potter A, Singh A.	Related Articles,
	Effects of nicotinic stimulation on cognitive performance. Curr Opin Pharmacol. 2004 Feb;4(1):36-46. PMID: 15018837 [PubMed - in process]

2:	Salin-Pascual RJ, Alcocer-Castillejos NV, Alejo-Galarza G.	Related Articles,
	Nicotine dependence and psychiatric disorders. Rev Invest Clin. 2003 Nov-Dec;55(6):677-93. PMID: 15011738 [PubMed - in process]

3:	Hellstrom-Lindahl E, Mousavi M, Ravid R, Nordberg A.	Related Articles,
	Reduced levels of Abeta 40 and Abeta 42 in brains of smoking controls and Alzheimer's patients. Neurobiol Dis. 2004 Mar;15(2):351-60. PMID: 15006705 [PubMed - in process]

4:	Myers CS, Robles O, Kakoyannis AN, Sherr JD, Avila MT, Blaxton TA, Thaker GK.	Related Articles,
	Nicotine improves delayed recognition in schizophrenic patients. Psychopharmacology (Berl). 2004 Mar 2 [Epub ahead of print] PMID: 14997272 [PubMed - as supplied by publisher]

5:	Sharp B, Yatsula M, Fu Y.	Related Articles,
	Effects of galantamine, a nicotinic allosteric potentiating ligand, on nicotine-induced catecholamine release in hippocampus and nucleus accumbens of rats. J Pharmacol Exp Ther. 2004 Feb 9 [Epub ahead of print] PMID: 14769831 [PubMed - as supplied by publisher]

6:	Liu Q, Zhao B.	Related Articles,
	Nicotine attenuates beta-amyloid peptide-induced neurotoxicity, free radical and calcium accumulation in hippocampal neuronal cultures. Br J Pharmacol. 2004 Feb;141(4):746-54. Epub 2004 Feb 02. PMID: 14757701 [PubMed - in process]

7:	Nordberg A.	Related Articles,
	Toward an early diagnosis and treatment of Alzheimer's disease. Int Psychogeriatr. 2003 Sep;15(3):223-37. PMID: 14756159 [PubMed - in process]

8:	Newhouse P, Singh A, Potter A.	Related Articles,
	Nicotine and nicotinic receptor involvement in neuropsychiatric disorders. Curr Top Med Chem. 2004;4(3):267-82. PMID: 14754447 [PubMed - in process]

9:	Di Angelantonio S, Bernardi G, Mercuri NB.	Related Articles,
	Donepezil modulates nicotinic receptors of substantia nigra dopaminergic neurones. Br J Pharmacol. 2004 Feb;141(4):644-52. Epub 2004 Jan 26. PMID: 14744806 [PubMed - in process]

10:	Moore SA, Huckerby TN, Gibson GL, Fullwood NJ, Turnbull S, Tabner BJ, El-Agnaf OM, Allsop D.	Related Articles,
	Both the D-(+) and L-(-) enantiomers of nicotine inhibit Abeta aggregation and cytotoxicity. Biochemistry. 2004 Jan 27;43(3):819-26. PMID: 14730987 [PubMed - in process]

11:	Kostrzewa RM, Segura-Aguilar J.	Related Articles,
	Novel mechanisms and approaches in the study of neurodegeneration and neuroprotection. a review. Neurotox Res. 2003;5(6):375-83. Review. PMID: 14715440 [PubMed - indexed for MEDLINE]

12:	Lemay S, Chouinard S, Blanchet P, Masson H, Soland V, Beuter A, Bedard MA.	Related Articles,
	Lack of efficacy of a nicotine transdermal treatment on motor and cognitive deficits in Parkinson's disease. Prog Neuropsychopharmacol Biol Psychiatry. 2004 Jan;28(1):31-9. PMID: 14687854 [PubMed - indexed for MEDLINE]

13:	Arias E, Ales E, Gabilan NH, Cano-Abad MF, Villarroya M, Garcia AG, Lopez MG.	Related Articles,
	Galantamine prevents apoptosis induced by beta-amyloid and thapsigargin: involvement of nicotinic acetylcholine receptors. Neuropharmacology. 2004 Jan;46(1):103-14. PMID: 14654102 [PubMed - in process]

14:	Hayslett RL, Tizabi Y.	Related Articles,
	Effects of donepezil on DOI-induced head twitch response in mice: implications for Tourette syndrome. Pharmacol Biochem Behav. 2003 Dec;76(3-4):409-15. PMID: 14643839 [PubMed - in process]

15:	Mousavi M, Hellstrom-Lindahl E, Guan ZZ, Shan KR, Ravid R, Nordberg A.	Related Articles,
	Protein and mRNA levels of nicotinic receptors in brain of tobacco using controls and patients with Alzheimer's disease. Neuroscience. 2003;122(2):515-20. PMID: 14614915 [PubMed - indexed for MEDLINE]

16:	Tan EK, Tan C, Fook-Chong SM, Lum SY, Chai A, Chung H, Shen H, Zhao Y, Teoh ML, Yih Y, Pavanni R, Chandran VR, Wong MC.	Related Articles,
	Dose-dependent protective effect of coffee, tea, and smoking in Parkinson's disease: a study in ethnic Chinese. J Neurol Sci. 2003 Dec 15;216(1):163-7. PMID: 14607318 [PubMed - indexed for MEDLINE]

17:	Hook VY, Reisine TD.	Related Articles,
	Cysteine proteases are the major beta-secretase in the regulated secretory pathway that provides most of the beta-amyloid in Alzheimer's disease: role of BACE 1 in the constitutive secretory pathway. J Neurosci Res. 2003 Nov 1;74(3):393-405. PMID: 14598316 [PubMed - indexed for MEDLINE]

18:	White HK, Levin ED.	Related Articles,
	Chronic transdermal nicotine patch treatment effects on cognitive performance in age-associated memory impairment. Psychopharmacology (Berl). 2004 Feb;171(4):465-71. Epub 2003 Oct 08. PMID: 14534771 [PubMed - in process]

19:	Lemay S, Blanchet P, Chouinard S, Masson H, Soland V, Bedard MA.	Related Articles,
	Poor tolerability of a transdermal nicotine treatment in Parkinson's disease. Clin Neuropharmacol. 2003 Sep-Oct;26(5):227-9. PMID: 14520160 [PubMed - indexed for MEDLINE]

20:	Doggrell SA, Evans S.	Related Articles,
	Treatment of dementia with neurotransmission modulation. Expert Opin Investig Drugs. 2003 Oct;12(10):1633-54. Review. PMID: 14519085 [PubMed - indexed for MEDLINE]

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Mar 15 2004 17:59:45

b. Accidental deaths caused by physicians per year is 120,000.

I'm not sure where the figure of 120,000 came from, but I believe I read the original article in the Journal of the American Medical Association which cited the the numbers in the following abstract. The hour is too late for me to hunt it down.

BTW, don't misunderstand all docs as being politically correct and disregarding common sense, when many totally agree with self-defense as in the Second Amendment and are only worried about meritless lawsuits.

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1: Eff Clin Pract. 2000 Nov-Dec;3(6):277-83. Related Articles,

How many deaths are due to medical error? Getting the number right.

Sox Jr HC, Woloshin S.

Dartmouth Medical School, Hanover, NH, USA. harold.c.sox@dartmouth.edu

CONTEXT: The Institute of Medicine (IOM) report on medical errors created an intense public response by stating that between 44,000 and 98,000 hospitalized Americans die each year as a result of preventable medical errors. OBJECTIVE: To determine how well the IOM committee documented its estimates and how valid they were. METHODS: We reviewed the studies cited in the IOM committee's report and related published articles. RESULTS: The two studies cited by the IOM committee substantiate its statement that adverse events occur in 2.9% to 3.7% of hospital admissions. Supporting data for the assertion that about half of these adverse events are preventable are less clear. In fact, the original studies cited did not define preventable adverse events, and the reliability of subjective judgments about preventability was not formally assessed. The committee's estimate of the number of preventable deaths due to medical errors is least substantiated. The methods used to estimate the upper bound of the estimate (98,000 preventable deaths) were highly subjective, and their reliability and reproducibility are unknown, as are the methods used to estimate the lower bound (44,000 deaths). CONCLUSION: Using the published literature, we could not confirm the Institute of Medicine's reported number of deaths due to medical errors. Due to the potential impact of this number on policy, it is unfortunate that the IOM's estimate is not well substantiated.

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PMID: 11151524 [PubMed - indexed for MEDLINE]

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Mar 15 2004 17:59:45

pooty parper

Honest honey!
It’s heart medicine!

Even a small amount of alcohol gives me a headache so I don't drink & I am safe from the bad effects as well as the good.

I am a member of the "take it of leave it club". I noticed in Feymann's biography that he quit the minute he noticed an urge to walk into a bar and start drinking. A good idea in his case. The benefits of light to moderate drinking are cancelled if alcoholism or heavy drinking is the result. Likewise, if other systems like the liver shut down, drinking has to go as well.

The benefits of light to moderate drinking extend outside the area of ingested chemicals. Many of us use a drink (or a smoke) as a means of relaxation. Being able to stand down and relax a bit every day is a life extender. Interesting that the creator set it up so that there are so many paradoxes, but thats the way it is. But one can only do this when one is the master of one's own fate. When smoking, drinking, or drug use take over one's life, (or becomes the focal point of one's life) then complete termination and rehab are in order. Take care everyone, now, it must be 5 o'clock somewhere.

My practice is to dispose of all dead vegetarians promptly

lol

I would think they don't have anything to generate any motivation in their life, or they were just lazy slobs in the first place.

I think moderate drinkers drink for excitement, and weed worshippers do their stuff to mellow out. I'm not much on mellow people. lol