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Hairy Skin From Mouse Stem Cells May Hold Cure for Baldness
The Economic Times ^ | Jan 03, 2018

Posted on 01/03/2018 12:49:27 PM PST by nickcarraway

In a finding that may provide potential cure for baldness, researchers have used stem cells from mice to develop a skin patch that is complete with hair follicles in a laboratory.

Using the skin model, the scientists developed both the epidermis (upper) and dermis (lower) layers of skin, which grow together in a process that allows hair follicles to form the same way as they would in a mouse's body.

The novel skin tissue more closely resembles natural hair than existing models and may prove useful for testing drugs, understanding hair growth, and reducing the practice of animal testing, the researchers said.

"You can see the organoids with your naked eye," said Karl Koehler, Assistant Professor at the Indiana University.

"It looks like a little ball of pocket lint that floats around in the culture medium. The skin develops as a spherical cyst, and then the hair follicles grow outward in all directions, like dandelion seeds."

In the study, published in Cell Reports, Koehler and team originally began using pluripotent stem cells from mice, which can develop into any type of cells in the body, to create organoids -- miniature organs in vitro -- that model the inner ear. 10 Bollywood celebrities with Miss India titleCRITICSUNION Free Santa Clara Real Estate Workshop!Rich Dad Education Recommended By Colombia

But they discovered that they were generating skin cells in addition to inner ear tissue. Thus, they decided to coax the cells into sprouting hair follicles.

Moreover, they found that mouse skin organoid technique could be used as a blueprint to generate human skin organoids.

"It could be potentially a superior model for testing drugs, or looking at things like the development of skin cancers, within an environment that's more representative of the in vivo microenvironment," Koehler noted.


TOPICS: Health/Medicine; Pets/Animals; Science
KEYWORDS: baldness; duplicate

1 posted on 01/03/2018 12:49:27 PM PST by nickcarraway
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To: nickcarraway

I guess mouse hair is better than no hair at all.


2 posted on 01/03/2018 12:50:49 PM PST by WayneS (An appeaser is one who feeds a crocodile, hoping it will eat him last. - Winston Churchill)
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To: nickcarraway

So rat stem cells for baldness is the next fad. What could possibly go wrong using rat stem cells? Hehehehe


3 posted on 01/03/2018 12:52:12 PM PST by Parley Baer
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To: nickcarraway

https://freerepublic.com/focus/f-chat/3618875/posts


4 posted on 01/03/2018 12:52:24 PM PST by Red Badger (Road Rage lasts 5 minutes. Road Rash lasts 5 months!.....................)
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To: nickcarraway
Initial results look promising, although still a way to go.


5 posted on 01/03/2018 12:52:35 PM PST by C210N (It is easier to fool the people than convince them that they have been fooled)
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To: WayneS

Agree - bald or mouse hair is some choice...


6 posted on 01/03/2018 12:53:25 PM PST by rigelkentaurus
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To: WayneS

Bald mice rejoice!................


7 posted on 01/03/2018 12:53:31 PM PST by Red Badger (Road Rage lasts 5 minutes. Road Rash lasts 5 months!.....................)
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To: nickcarraway

Rogaine, meet Ratgaine.


8 posted on 01/03/2018 12:56:28 PM PST by A Formerly Proud Canadian (I once was blind but now I see...)
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To: rigelkentaurus
Works better for a few folks, apparently.


9 posted on 01/03/2018 12:56:49 PM PST by C210N (It is easier to fool the people than convince them that they have been fooled)
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Comment #10 Removed by Moderator

To: nickcarraway

There are benefits to being bald

$20 every five years for a new shaver
No design considerations
Haven’t bought shampoo in 30 years
When daughter is crying because she’s out of conditioner, you simply say “what’s conditioner?”
Zero cost for hair styling
quick showers
Hair dryer?
Get to wear hats anytime
Get really cool vent sunburns from helmet after a 100 mile bike ride
No such thing as bed head, hat hair or helmet hair

There may be some guys who cry because they are bald. I have never cared enough to care.


11 posted on 01/03/2018 1:00:36 PM PST by cyclotic (Trump tweets are the only news source you can trust.)
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To: nickcarraway

I understand there is only one adverse side effect, an uncontrollable desire for cheese.


12 posted on 01/03/2018 1:00:53 PM PST by Mastador1 (I'll take a bad dog over a good politician any day!)
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To: nickcarraway

13 posted on 01/03/2018 1:05:13 PM PST by Vendome (I've Gotta Be Me - https://www.youtube.com/watch?v=wH-pk2vZG2M)
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To: Mastador1
How does this cure baldness?
14 posted on 01/03/2018 1:07:58 PM PST by EQAndyBuzz (Delusional - Adjective, Describes a Democrat or member of the MSM)
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To: nickcarraway

Assuming this works, you’ll be chased by cats all over the place.


15 posted on 01/03/2018 1:28:23 PM PST by I want the USA back (Lying Media: willing and eager allies of hate-America savages.)
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To: nickcarraway

I’ve always said, “ If you’re a man with a good full head of hair, you may have way to much estrogen coursing through your body.”


16 posted on 01/03/2018 1:55:28 PM PST by pacobell
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To: nickcarraway

Be sure to check for mouse allergies FIRST!


17 posted on 01/03/2018 2:03:44 PM PST by G Larry (There is no great virtue in bargaining with the Devil)
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To: Parley Baer

What next? A return to GOAT GLANDS?


18 posted on 01/03/2018 2:51:26 PM PST by Ruy Dias de Bivar
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To: nickcarraway

[Monty Python - The Mouse Problem]
https://www.youtube.com/watch?v=uK92NYwBMts


19 posted on 01/03/2018 3:35:58 PM PST by HLPhat ("TO SECURE THESE RIGHTS" -- Government with any other purpose is not American.)
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To: Ruy Dias de Bivar

*** What next? A return TO GOAT GLANDS? ***

Growing up in TX, I always loved stories about this guy:

https://www.legendsofamerica.com/john-brinkley/


20 posted on 01/04/2018 1:34:50 AM PST by sockmonkey
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