Free Republic
Browse · Search
General/Chat
Topics · Post Article

Skip to comments.

HIV breakthrough as cancer drug could hold secret to curing the virus
www.mirror.co.uk ^ | 00:05, 1 DEC 2017 Updated10:52, 1 DEC 2017 | ByAmy-Clare Martin

Posted on 12/01/2017 6:12:44 AM PST by Red Badger

Doctors using a treatment called nivolumab on a lung cancer patient with Aids noticed a “drastic and persistent” decrease in infected white blood cells

A new cancer drug could “cure” HIV, a revolutionary study suggests.

Doctors using a treatment called nivolumab on a lung cancer patient with Aids noticed a “drastic and persistent” decrease in infected white blood cells.

The findings have raised hopes that drugs could one day eradicate the HIV virus, which attacks the immune system and cur­­rently has no cure.

At present, those infected must take anti-HIV drugs for the rest of their lives to stop the virus replicating.

Prof Fabrice Andre from the Institut Gustave Roussy in Villejuif, France, said today: “Although this is a single case study, it is an exciting result.

“Anti-HIV drugs usually stop virus replication but don’t cure the patients who still have reservoirs of the virus.

“This study generates the hypothesis that drugs that make the virus disappear could, perhaps, cure patients.”

Nivolumab, which has no known side effects, appeared to cause a dramatic reduction in reservoirs of HIV infected cells in the test-patient as well as an increase in T-cells which fight cancer.

Prof Jean-Philippe Spano, who led the medical team at the Pitie-Salpetriere Hospital in Paris, said: “This is the first demonstration of this mechanism in humans. It could have implications for HIV patients.

(Excerpt) Read more at mirror.co.uk ...


TOPICS: Business/Economy; Health/Medicine; Science; Society
KEYWORDS: aids; cancer; chemo; cure; hiv; medicine; oncology; opdivo; pharma; virus
Navigation: use the links below to view more comments.
first 1-2021-28 next last

1 posted on 12/01/2017 6:12:45 AM PST by Red Badger
[ Post Reply | Private Reply | View Replies]

To: Red Badger

Syphilis another diseases have gotten worse. Scummy people engaging in Random sexWill continue to spread social diseases.

Cure schmure


2 posted on 12/01/2017 6:15:35 AM PST by a fool in paradise (Did Barack Obama denounce Communism and dictatorships when he visited Cuba as a puppet of the State?)
[ Post Reply | Private Reply | To 1 | View Replies]

To: Red Badger

Nivolumab (and other checkpoint inhibitors) work by activating T cells (the cells that are infected by HIV).

The mechanism seems to make sense! But we need to see via clinical trials that these drugs really work and for what classes of AIDS patients.


3 posted on 12/01/2017 6:21:27 AM PST by Honorary Serb (Kosovo is Serbia! Free Srpska! Abolish ICTY!)
[ Post Reply | Private Reply | To 1 | View Replies]

To: Red Badger
If accurate and repeatable, this is one of the best pieces of real medical news in a long time. Interesting.

Also the latest news over freeze dried plasma use has been very interesting. The implications are hugh and series.

A bag of freeze dried plasma can also be dry formulated with virus immunizations and other medicines. Just add water (sterile saline).

4 posted on 12/01/2017 6:23:06 AM PST by blackdog
[ Post Reply | Private Reply | To 1 | View Replies]

To: Red Badger
Nivolumab, which has no known side effects

Nonsense

5 posted on 12/01/2017 6:23:45 AM PST by aposiopetic
[ Post Reply | Private Reply | To 1 | View Replies]

To: Honorary Serb

IIRC, I could be mistaken, but didn’t Trump Administration make it easier to bring new drugs to market faster?...................


6 posted on 12/01/2017 6:24:45 AM PST by Red Badger (Road Rage lasts 5 minutes. Road Rash lasts 5 months!.....................)
[ Post Reply | Private Reply | To 3 | View Replies]

To: Red Badger

Nope. How many “cures” have been touted over the past decade which turned out to be false?

As long as the sodomite “community” continues to foster an ideal environment for this virus, it will continue to morph into super strains defying a cure.


7 posted on 12/01/2017 6:34:01 AM PST by fwdude (Why is it that the only positive things to come out of LGBT organizations are their AIDS tests?)
[ Post Reply | Private Reply | To 1 | View Replies]

To: blackdog

Yes, I was very interested in the freeze dried plasma announcement as well.


8 posted on 12/01/2017 6:35:11 AM PST by rlmorel (Liberals: American Liberty is the egg that requires breaking to make their Utopian omelette.)
[ Post Reply | Private Reply | To 4 | View Replies]

To: Red Badger

Sometimes real life mimics fiction. Remember in I Am Legend, scientists cured cancer by modifying the rabies virus, but created a horrific monster strain of human.

I can’t see “no side effects” as being realistic.


9 posted on 12/01/2017 6:37:23 AM PST by fwdude (Why is it that the only positive things to come out of LGBT organizations are their AIDS tests?)
[ Post Reply | Private Reply | To 1 | View Replies]

To: Red Badger

It has been over 36 months since I was diagnosed with stage four coon cancer, I have used no chemo, no radiation only Apricots, Apricot kernels, my own saliva and prayer, and I am doing fine and looking forward to CHRISTmas and then 90 days later my 74th birthday.

Cancer is a vitamin deficiency.


10 posted on 12/01/2017 6:41:14 AM PST by Bob Celeste
[ Post Reply | Private Reply | To 1 | View Replies]

To: rlmorel

Even though it was old WWII technology. Which for me makes me feel better about it.


11 posted on 12/01/2017 6:45:45 AM PST by blackdog
[ Post Reply | Private Reply | To 8 | View Replies]

To: aposiopetic

The most common side effects of nivolumab for melanoma patients include:

Fatigue
Joint or muscle pain
Diarrhea
Rash or itchy skin
Nausea
The most common side effects of nivolumab for NSCL patients include:

Fatigue
Joint or muscle pain
Decreased appetite
Cough
Constipation
The most common side effects of nivolumab for renal cell carcinoma patients include:

Fatigue
Shortness of breath
Joint or muscle pain
Decreased appetite
Rash
Diarrhea
Cough
Constipation
Rash or itchy skin
Nausea
The most common side effects of nivolumab for Hodgkin lymphoma patients include:

Fatigue
Upper respiratory infection
Fever

https://www.cancercenter.com/cancer-drugs/nivolumab/


12 posted on 12/01/2017 6:46:53 AM PST by Delta 21 (Build The Wall !! Jail The Cankle !!)
[ Post Reply | Private Reply | To 5 | View Replies]

To: Red Badger
This drug sounds promising for cancer. HIV is a virus that the immune compromised get hence the homosexual and IV drug addict affliction.

As usual NEVER trust the media, especially on medical news.
Long list of side effects for this drug: Opdivo

13 posted on 12/01/2017 6:48:34 AM PST by Varda (Liberalism IS hate)
[ Post Reply | Private Reply | To 1 | View Replies]

To: Red Badger

In about 1989 I repeated the Surgeon General’s assertion that there’d be no cure in the next 10 years, and emphasized I expected none in 20 years.

We’re nearing 30 years, and I doubt this will be declared a “cure” any time soon.


14 posted on 12/01/2017 6:56:18 AM PST by G Larry (There is no great virtue in bargaining with the Devil)
[ Post Reply | Private Reply | To 1 | View Replies]

To: Red Badger

“IIRC, I could be mistaken, but didn’t Trump Administration make it easier to bring new drugs to market faster?...................”

Lets hope so. Under previous administrations it would take our wonderful government 20 years to approve known cures already in world wide use. Its a miracle we have penicillin or polio vaccine for example the way FDA works. May they be stricken themselves.


15 posted on 12/01/2017 6:59:53 AM PST by Bonemaker (White Southerners have been under attack since 1860.)
[ Post Reply | Private Reply | To 6 | View Replies]

To: blackdog

I always found the accounts interesting, that they would have these wounded guys who lost a lot of blood so pumped up with plasma that their faces looked like people who had been painted waxy-white because they has lost so many blood cells...it was a characteristic look you saw everywhere there were wounded men.


16 posted on 12/01/2017 7:17:56 AM PST by rlmorel (Liberals: American Liberty is the egg that requires breaking to make their Utopian omelette.)
[ Post Reply | Private Reply | To 11 | View Replies]

To: rlmorel
Survival in a trauma involving serious damage and bleeding all boils down to one thing.

Maintaining hydraulic pressure. We are machines. The machine's components can only perform with a tightly regulated range of hydraulic pressures. That and a barely maintained level of red blood cells carrying oxygen.

That is why you don't poke a dead person's face. It makes it very difficult to pop the dent back out for the funeral.

17 posted on 12/01/2017 7:23:49 AM PST by blackdog
[ Post Reply | Private Reply | To 16 | View Replies]

To: aposiopetic

Yep - anyone who watches TV knows all the ...umab variations have a lot of side effects - I guess it’s a coin flip about what one is willing to risk to avoid a different inevitable...


18 posted on 12/01/2017 7:27:31 AM PST by trebb (Where in the the hell has my country gone?)
[ Post Reply | Private Reply | To 5 | View Replies]

To: Red Badger

So what will this cost tax payers, $100,000 per vial?


19 posted on 12/01/2017 7:30:57 AM PST by Grampa Dave (The fastest way to drain the DC swamp is to simply expose it! Sunlight does aid in evaporation!)
[ Post Reply | Private Reply | To 1 | View Replies]

To: aposiopetic

From Wikipedia:

Side effects[edit]

The drug label contains warnings with regard to increased risks of severe immune-mediated inflammation of the lungs, the colon, the liver, the kidneys (with accompanying kidney dysfunction), as well as immune-mediated hypothyroidism and hyperthyroidism.[2]

In clinical trials for melanoma, the following side effects occurred in more than 10% of subjects and more frequently than with chemotherapy alone: rash and itchy skin, cough, upper respiratory tract infections, and peripheral edema. Other clinically important side effects with less than 10% frequency were ventricular arrhythmia, inflammation of parts of the eye (iridocyclitis), infusion-related reactions, dizziness, peripheral and sensory neuropathy, peeling skin, erythema multiforme, vitiligo, and psoriasis.[2]

In clinical trials for lung cancer, the following side effects occurred in more than 10% of subjects and more frequently than with chemotherapy alone: fatigue, weakness, edema, fever, chest pain, generalized pain, shortness of breath, cough, muscle and joint pain, decreased appetite, abdominal pain, nausea and vomiting, constipation, weight loss, rash, and itchy skin.[2]

Levels of electrolytes and blood cells counts were also disrupted.[2]

https://en.wikipedia.org/wiki/Nivolumab

Looks like a bunch of side effects.


20 posted on 12/01/2017 7:32:34 AM PST by NorthMountain (... the right of the people to keep and bear arms shall not be infringed)
[ Post Reply | Private Reply | To 5 | View Replies]


Navigation: use the links below to view more comments.
first 1-2021-28 next last

Disclaimer: Opinions posted on Free Republic are those of the individual posters and do not necessarily represent the opinion of Free Republic or its management. All materials posted herein are protected by copyright law and the exemption for fair use of copyrighted works.

Free Republic
Browse · Search
General/Chat
Topics · Post Article

FreeRepublic, LLC, PO BOX 9771, FRESNO, CA 93794
FreeRepublic.com is powered by software copyright 2000-2008 John Robinson