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Have scientists discovered the elixir of youth? Hormone extends lifespan by 40%
Daily Mail ^ | 1/14/16 | Lizzie Parry

Posted on 01/16/2016 10:05:02 AM PST by UnwashedPeasant

A team at Yale School of Medicine have identified a hormone, produced by the thymus glad, extends lifespan by 40 per cent.

Their findings reveal increased levels of the hormone, known as FGF21, protects the immune system against the ravages of age.

Researchers said the study could have implications in the future for improving immune function in the elderly, for obesity, and for diseases such as cancer and type 2 diabetes.

When it is functioning normally, the thymus produces new T cells for the immune system.

But with age, the gland becomes fatty and loses its ability to produce the vital cells.

This loss of new T cells in the body is one cause of increased risk of infections and certain cancers in the elderly.

Researchers led by Vishwa Deep Dixit, professor of comparative medicine and immunobiology at Yale, studied transgenic mice with elevated levels of FGF21.

They blocked the gene's function, before studying the impact of decreasing levels of FGF21 on the immune system.

Their results showed that increasing the level of FGF21 in old mice protected the thymus from age-related fatty degeneration and increased the ability of the thymus to produce new T cells.

Meanwhile, FGF21 deficiency accelerated the degeneration of the thymus in old mice.

Professor Dixit said: 'We found that FGF21 levels in thymic epithelial cells is several fold higher than in the liver, therefore FGF21 acts within the thymus to promote T cell production.

(Excerpt) Read more at dailymail.co.uk ...


TOPICS: Health/Medicine
KEYWORDS: hormone; hormones
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If the therapeutic effect comes from defatting the thymus, there might be other ways to do it, such as taking betaine.
1 posted on 01/16/2016 10:05:02 AM PST by UnwashedPeasant
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To: UnwashedPeasant

Do you know how to make a hormone ?

Refuse to pay her.


2 posted on 01/16/2016 10:06:36 AM PST by UCANSEE2 (Lost my tagline on Flight MH370. Sorry for the inconvenience.)
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To: UnwashedPeasant

There is no limit to the money that will be spent, and the aborted babies to be dissected and used in experiments that will stop the ruling elite from trying to obtain immortality.


3 posted on 01/16/2016 10:09:22 AM PST by UCANSEE2 (Lost my tagline on Flight MH370. Sorry for the inconvenience.)
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To: UCANSEE2

If not as many people die, where do you put them all.
Possibly this could spur planetary immigration.


4 posted on 01/16/2016 10:13:06 AM PST by tet68 ( " We would not die in that man's company, that fears his fellowship to die with us...." Henry V.)
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To: UnwashedPeasant

"And so, you see, I will never die."

5 posted on 01/16/2016 10:13:44 AM PST by ClearCase_guy (I don't know what Claire Wolfe is thinking but I know what I am thinking.)
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To: UnwashedPeasant

I think that the effect is not from defatting the thymus, but from either preventing thymic cells from dying with age or by inducing cells in the thymus to become a certain cell type. The full article said that the mechanism of protection by the hormone FGF21 remains to be elucidated. But that would be my working hypothesis.


6 posted on 01/16/2016 10:15:17 AM PST by exDemMom (Current visual of the hole the US continues to dig itself into: http://www.usdebtclock.org/)
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To: UnwashedPeasant

7 posted on 01/16/2016 10:16:18 AM PST by martin_fierro (< |:)~)
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To: UCANSEE2

Lol from hubby and myself.


8 posted on 01/16/2016 10:16:54 AM PST by jonathonandjennifer
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To: tet68
If not as many people die, where do you put them all.

The reason there are 7 billion (or whatever) people on earth now is that better medicine extends the lifespan, and the fertility rate has not dropped accordingly. Most especially, the effect occurs because children who, in previous eras, would have died before the age of 5 now survive into adulthood and then have children.

I do not think that preventing immune system aging would have that much of an effect, because the people whose lifespans would be increased are already beyond reproductive age, since the immune system starts its major decline after age 65.

9 posted on 01/16/2016 10:20:36 AM PST by exDemMom (Current visual of the hole the US continues to dig itself into: http://www.usdebtclock.org/)
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To: UnwashedPeasant

Is betaine what they’re talking about?


10 posted on 01/16/2016 10:25:09 AM PST by STJPII
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To: exDemMom

God has numbered man’s years to 120. It won’t matter what anyone does.


11 posted on 01/16/2016 10:26:06 AM PST by Bulwyf
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To: UnwashedPeasant

If we keep electing people like Obama and Hillary, who would want to use this hormone?


12 posted on 01/16/2016 10:27:00 AM PST by Michael.SF. (That was the gift the president gave us, the gift of happiness, of being together,' Cindy Sheehan")
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To: UnwashedPeasant

100+ is when you can really start enjoying life.


13 posted on 01/16/2016 10:30:42 AM PST by Berlin_Freeper
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To: UCANSEE2

A classic!


14 posted on 01/16/2016 10:35:34 AM PST by Chainmail (A simple rule of life: if you can be blamed, you're responsible.)
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To: STJPII
"Is betaine what they're talking about?"

No, I threw that it. But I think it was a bum steer.

15 posted on 01/16/2016 10:36:29 AM PST by UnwashedPeasant (A slave is one who waits for someone to come and free him.)
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To: UnwashedPeasant

No, thanks. I couldn’t bear 40% extra time on this miserable planet.


16 posted on 01/16/2016 10:37:34 AM PST by Politicalkiddo ("If this poor life of mine could save you, [my country] how willingly would I make the sacrifice!")
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To: Berlin_Freeper

100 is the new 80


17 posted on 01/16/2016 10:49:08 AM PST by Noumenon (Resistance. Restoration. Retribution.)
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To: tet68
If not as many people die, where do you put them all.

There is enough food to feed everyone on the planet, and there is enough room for everyone to live comfortably.

The problem is that we don't distribute the food or living space properly.

18 posted on 01/16/2016 11:05:59 AM PST by UCANSEE2 (Lost my tagline on Flight MH370. Sorry for the inconvenience.)
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To: UCANSEE2

And, if you extend life at the far end of the span another 40%, most can’t work so where does the $$$ to live on come from?
I’ll pass and just leave it up to a power greater than I to decide.....


19 posted on 01/16/2016 11:15:52 AM PST by matginzac
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To: UnwashedPeasant

Now Social Security is really screwed.


20 posted on 01/16/2016 11:26:53 AM PST by CrazyIvan (Hey Pope Francis- The Gospels are not Matthew, Marx, Luke and John.)
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