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Branded Curcumin Matches Effects of Prozac on Depression
WholeFoods Magazine ^ | 7/24/13 | NA

Posted on 07/28/2013 11:19:21 AM PDT by neverdem

Chester, NJ—A recent clinical trial published in Phytotherapy Research indicated that a high-absorption curcumin (BCM-95 from Dolcas Biotech, based here) had similar effects as a generic form of Prozac (fluoxetine) on depression, sans the adverse effects.

“It is a novel and surprising application for this natural medicine,” said Ajay Goel, Ph.D., Baylor Research Institute and Charles A Sammons Cancer Center, Baylor University Medical Center and study co-author. “People with depression have higher levels of inflammation in the brain. Also, people with depression have lower levels of neurogenesis in the brain, meaning they make fewer new brain cells than people with no history of depression. Curcumin is both a potent anti-inflammatory agent and a powerful stimulator for neurogenesis.”

The three-pronged study included 60 volunteers diagnosed with major depressive disorder, with 20 people taking either BCM-95 Curcumin (500 mg capsules twice daily); 20 people taking fluoxetine 20 mg daily; or 20 people taking a combination of BCM-95 Curcumin twice daily with fluoxetine once daily. Their level of depression was assessed using the clinically validated Hamilton Rating Scale for Depression (HAM-D17), which is used to evaluate one’s mood, feelings of guilt, feelings of suicide and other symptoms.

After six weeks, the research showed that curcumin was well tolerated by all of the subjects. The proportion of responders with improved depression symptoms was higher in the combination group (77.8%) than in the fluoxetine (64.7%) and the curcumin (62.5%) groups. However, the data also showed that BCM-95 Curcumin worked as well as fluoxetine in terms of changes in the HAM-D17 score from baseline through six weeks of treatment.

The study was the first human clinical indication that Curcumin can be used as an effective and safe treatment for patients with depression, though it cannot be considered a medical treatment at this time.

Published in WholeFoods Magazine, October 2013 (online 7/24/13)


TOPICS: Health/Medicine
KEYWORDS: alzheimers; antiinflammatory; bcm95; braininflammation; curcumin; depression; inflammation; osteoporosis; prozac; same; tumeric; turmeric
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To: Eepsy

More or less... there are some disputes over details but that’s the general thrust of the fall of the creation. The old earth and young earth creation theological camps probably won’t see eye to eye anytime sooner than the return of the Lord, but both perceive a metaphysical shift, rooted in a spiritual shift, that came with men accepting the sin of the rebellious angels. And one important point to note, as in the case of the man born blind that Jesus healed, is that not all suffering is due to one’s own personal sins. It is part of being in a battle zone.


41 posted on 07/28/2013 8:18:31 PM PDT by HiTech RedNeck (Whatever promise that God has made, in Jesus it is yes. See my page.)
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To: who_would_fardels_bear

Hopefully others have presented better answers than I have furnished. But I think to sum up, yep we are in a spiritual war zone. God folds suffering into His plan in an omniscient, omnipotent manner to, among other things, show people the need of returning to God even while refraining from forcing their will. Really, to some people God could never do anything to satisfy them. If God forced their wills then they’d call God a manipulative tyrant. If God refrains then they’d accuse God of being vague and difficult. Now if you take this as an accusation to sufferers that they have somehow earned their suffering through sinning, you have warped my message. Because mercy is also folded into His plan.


42 posted on 07/28/2013 8:26:12 PM PDT by HiTech RedNeck (Whatever promise that God has made, in Jesus it is yes. See my page.)
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To: Mad Dawg

Well Dawg, you got to see what happens when scientific pursuit worships itself and forgets the roots it once had in the pursuit of the divine. We can have valid arguments over “HOW” God did something, but not over “WHETHER” God did something, unless we want to try to wrench ourselves artificially out of the hands of God.


43 posted on 07/28/2013 8:32:10 PM PDT by HiTech RedNeck (Whatever promise that God has made, in Jesus it is yes. See my page.)
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To: EarlT357
“Big Phrama”? You signed up *today* to tell us about “Big Pharma”? Please let us know when a member of your family is diagnosed with,say,advanced brain cancer.He/she will surely,at your insistence,choose infusions of liquefied alfalfa sprouts instead of any of the poisons produced by “Big Pharma”.
44 posted on 07/28/2013 8:35:31 PM PDT by Gay State Conservative (If Obama Had A City It Would Look Like Detroit.)
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To: Gay State Conservative

ah, ignore the heckling trolls who have nothing but negative comments and nothing constructive to offer.


45 posted on 07/28/2013 8:41:52 PM PDT by HiTech RedNeck (Whatever promise that God has made, in Jesus it is yes. See my page.)
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To: HiTech RedNeck
I suppose you’re right.
46 posted on 07/28/2013 8:48:11 PM PDT by Gay State Conservative (If Obama Had A City It Would Look Like Detroit.)
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To: Gay State Conservative

They’re trying to trap your mind in a cage of surmises, without being challenged on their surmises. It is so easy to damn the good because it isn’t perfect and that’s an infantile, sinful game. It’s not as easy to figure out how to make the good better.


47 posted on 07/28/2013 8:50:23 PM PDT by HiTech RedNeck (Whatever promise that God has made, in Jesus it is yes. See my page.)
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To: HiTech RedNeck
the more exotic the placebo the better... i think there is a faith effect here

Frankly I don't care if it's "just a placebo" I want the pain to go away.

48 posted on 07/28/2013 11:33:43 PM PDT by null and void (You don't know what "cutting edge" means till you insult Mohammed.)
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To: HiTech RedNeck

Oh, that’s a massive huge 10-4 with whipped cream AND sprinkles!

Scientism is clearly a false religion as can be shown by the inductive process. In particular it weakens the mind. The unawareness that what a thing IS might be importantly different from what it is MADE OF, or that how a thing comes to be might be different from why or to what purpose it came to be ... this kind of unawareness is just sloppy. But it’s a sloppiness Scientism fosters.


49 posted on 07/29/2013 6:15:09 AM PDT by Mad Dawg (In te, Domine, speravi: non confundar in aeternum.)
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To: neverdem

The problem is that curcumin is not well absorbed.The only way I know of to enhance this is piperine, which is why I eat pepper before taking it.


50 posted on 07/29/2013 12:17:42 PM PDT by rmlew ("Mosques are our barracks, minarets our bayonets, domes our helmets, the believers our soldiers.")
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