My wife has been skipping her medicine one day a week to build up a stockpile in case of an emergency or a shortage. When she gets new medicine she replaces the pills she saved with the newer ones so she will always have the best shelf life possible.
If your wife’s meds are not narcotics or controlled substances, talk to your doc about putting in an emergency supply. Most docs are more conservative than you think. Of course, your insurance may not cover buying ahead.
As long as she is safe doing that, a couple years and a good backup is saved up. I think I’ll research our various meds for that possibility.