Posted on 11/22/2016 2:21:42 PM PST by Red Badger
Polyamines, such as spermidine, are polycationic aliphatic amines and are multifunctional. They serve vital roles in cell survival.
Spermidine synthase (SPDS) catalyzes the formation of spermidine from putrescine. Spermidine is a precursor to further polyamines, such as spermine and its structural isomer thermospermine.
Spermidine synchronizes an array of biological processes (such as Ca2+, Na+, K+ -ATPase) thus maintaining membrane potential and controlling intracellular pH and volume. Spermidine regulates biological processes, such as Ca2+ influx by glutamatergic N-methyl-d-aspartate receptor (NMDA receptor), which has been associated with nitric oxide synthase (NOS) and cGMP/PKG pathway activation and a decrease of Na+,K+-ATPase activity in cerebral cortex synaptosomes.
Spermidine is a longevity agent in mammals due to various mechanisms of action, which are just beginning to be understood. Autophagy is the main mechanism at the molecular level, but evidence has been found for other mechanisms, including inflammation reduction, lipid metabolism, and regulation of cell growth, proliferation and death.[2]
Spermidine has been tested and discovered to encourage hair shaft elongation and lengthen hair growth. Spermidine has also been found to “upregulate expression of the epithelial stem cell-associated keratins K15 and K19, and dose-dependently modulated K15 promoter activity in situ and the colony forming efficiency, proliferation and K15 expression of isolated human K15-GFP+ cells in vitro.”
Source: Wikipedia
Keto!
Of course, it has to be the only cheese that is good for you
Ultra Sharp Canadian Cheddar Aged 7 Years. I also like Bleu and several of the Italian cheeses. Mmmmm! Glorious cheese.
Yeah! I have a condition which can’t handle certain raw veggies. So I drown my sorrows by OD-ing on the garnishes. Throw in some cheesy, garlicky croutons, too.
So how come Shepard Smith and his ilk have such short life expectancies?
I knew an alcoholic who refused to drink water because fish **** in it.
Sperm what ?
I’m allergic to milk and cheese, but I still eat cheese. Super Sharp cheddar and Blue Cheese are my favorites.
I had the same thought.
There are other factors involved , shall we say.
Forget the croutons! Just eat garlic!...........
Excellent! There are so many great cheeses.
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>> “Why autocorrect knows polyamide and not polyamine, I don’t know” <<
All of these “helps” are trying to dumb us all down to the lowest level.
I once clicked on “Grammatic” in my word processor, and let it “correct” my letter.
Never again!
It came out looking like it was written by Goober from Mayberry.
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I hear you.
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>> “Forget the croutons! Just eat garlic!” <<
Yes!
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Sounds good to me!
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