Neanderthal genes gave modern humans an immunity boost and allergies
Posted on 01/07/2016 10:51:53 PM PST by SunkenCiv
When modern humans met Neanderthals in Europe and the two species began interbreeding many thousands of years ago, the exchange left humans with gene variations that have increased the ability of those who carry them to ward off infection. This inheritance from Neanderthals may have also left some people more prone to allergies. Researchers of the Max Planck Institute for Evolutionary Anthropology in Leipzig, Germany, and the Institut Pasteur and the CNRS in Paris, France, report about the discoveries in two independent studies, adding to evidence for an important role for interspecies relations in human evolution and specifically in the evolution of the innate immune system, which serves as the body's first line of defense against infection. "We found that interbreeding with archaic humans, the Neanderthals and Denisovans, has influenced the genetic diversity in present-day genomes at three innate immunity genes belonging to the human Toll-like-receptor family," says Janet Kelso of the Max Planck Institute for Evolutionary Anthropology in Leipzig, Germany. "These, and other, innate immunity genes present higher levels of Neanderthal ancestry than the remainder of the coding genome," adds Lluis Quintana-Murci of the Institut Pasteur and the CNRS in Paris. "This highlights how important introgression events, the movement of genes across species, may have been in the evolution of the innate immunity system in humans."
Earlier studies have shown that one to six percent of modern Eurasian genomes were inherited from ancient hominins, such as Neanderthal or Denisovans. Both new studies highlight the functional importance of this inheritance on Toll-like receptor (TLR) genes TLR1, TLR6, and TLR10. These TLR genes are expressed on the cell surface, where they detect and respond to components of bacteria, fungi, and parasites. These immune receptors are essential for eliciting inflammatory and anti-microbial responses and for activating an adaptive immune response.
(Excerpt) Read more at mpg.de ...
Interspecies Relations Boosted Modern Human Immunity
http://www.archaeology.org/news/4055-160107-neanderthal-denisovans-immunity
That settles it I am descended from Neanderthals . I don’t get many infections but I have a lot of allergies
I figured it out one time at a family reunion. ;’)
The sons of Seth found the girls sired by Cain’s descendants quite attractive?
Someone posted a picture of a Neanderthal man, thank God I look nothing like him but I do have allergies.
good god, the lying is thicker than ever.
Yes, I noticed that in message 7.
Hey, I missed my mark. Not intended for you. Sorry for the error.
Thanks, sorry.
Good!
this answers lots of questions.
Does that mean we aren’t all humans?
Did you eventually hit your target?
Nope. Hecky durn.
It was Shucky Dang in my day. :o)
Well, you must be deep southern and very, very old.
I am not.
Hecky durn.
I heard west texas has trees- do your Methodist’s allow for that kind of growth?
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